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https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/i1/CJB-2017-107.php
Various production strategies have been explored to overcome challenges associated with the oral delivery of therapeutic peptides and proteins. The goal of this review is to provide an overview of the current state of progress made towards the oral delivery of GLP-1 and its analogs in the treatment of T2DM, with special emphasis on the development of plant and food-grade bacterial delivery systems.
http://www.pharmtech.com/emerging-technologies-advance-oral-drug-delivery
Jun 02, 2018 · The technology could potentially be the key to solving oral delivery challenges for biologics such as insulin, antibodies, human growth hormones, peptides, and proteins (5). Rani’s robotic pill is a sophisticated device where the solid drug is placed inside tiny, hollow, dissolvable needles, assembled into a balloon-like structure and folded in the capsule.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835173/
Oral delivery technologies can be used to treat diseases of the gastrointestinal (GI) tract locally or to enable therapeutics to reach systemic circulation. For therapeutics to reach the bloodstream after oral administration, they must pass through the gastrointestinal (GI) tract and be absorbed.Author: Eric M Pridgen, Frank Alexis, Omid Cameron Farokhzad
https://www.researchandmarkets.com/reports/2640125/emerging_drug_delivery_technologies_profiles_of
This report highlights some of the emerging technologies designed to effectively delivery large molecular weight drugs such as antibody-based therapeutics, proteins, and peptides. Companies developing such technologies include Entrega, Extend Biosciences, and Solstice Biologics.
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1567-2018&volume=6&issue=4&spage=347
This review summarizes strategies and technologies that are being used to improve oral vaccine absorption. Peptides and proteins, which comprise important vaccine components, exhibit unfavorable physicochemical properties including degradation in the gastrointestinal tract, and poor transport across the intestinal wall, which hinder oral vaccine development.
https://www.marketwatch.com/press-release/global-oral-controlled-release-drug-delivery-technology-market-2020---industry-scenario-strategies-growth-factors-and-forecast-to-2025-2020-04-03
Apr 03, 2020 · The report provides a comprehensive analysis of the global Oral Controlled Release Drug Delivery Technology industry market by types, applications, players and regions.
https://www.sciencedirect.com/science/article/pii/S0734975014001116
A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules. ... (protein oral delivery) technology for oral delivery of insulin. ... Several oral delivery strategies have been proposed to enhance the permeation of protein and peptide molecules through the GIT. The aim of ...Author: Bibi F. Choonara, Yahya E. Choonara, Pradeep Kumar, Divya Bijukumar, Lisa C. du Toit, Viness Pillay
http://www.iptonline.com/articles/public/IPTNINE106NoPrint.pdf
DRUG FORMULATION & DELIVERY Innovations in Pharmaceutical Technology 107 to metabolism in the intestinal mucosa, where a penetration barrier prevents entry into cells. On the other hand, oral and colonic delivery have the advantage of delivering drugs through the intestinal tract to the hepatic portal vein, and then to the systemic circulation.File Size: 228KB
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