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https://www.ncbi.nlm.nih.gov/pubmed/30948824
1. Nat Biomed Eng. 2018 Jul;2(7):497-507. doi: 10.1038/s41551-018-0252-8. Epub 2018 Jun 25. Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours.Author: Bumwhee Lee, Kunwoo Lee, Shree Panda, Rodrigo Gonzales-Rojas, Anthony Chong, Vladislav Bugay, Hyo Mi...
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201914751
Jan 29, 2020 · Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier. Dr. Hyun Su Min. Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, …Author: Hyun Su Min, Hyun Jin Kim, Mitsuru Naito, Satomi Ogura, Kazuko Toh, Kotaro Hayashi, Beob Soo Kim, Sh...
https://www.nature.com/articles/s41467-019-13198-y
Nov 15, 2019 · We herein present novel materials and device technologies for drug delivery to brain tumors, i.e., a flexible, sticky, and biodegradable drug-loaded …Author: Jongha Lee, Hye Rim Cho, Gi Doo Cha, Hyunseon Seo, Hyunseon Seo, Seunghyun Lee, Chul Kee Park, Jin W...
https://www.ncbi.nlm.nih.gov/pubmed/31837821
Dec 06, 2019 · Direct nose-to-brain (N-to-B) delivery enables the rapid transport of drugs to the brain, while minimizing systemic exposure. The objective of this work was to engineer a nanocarrier intended to enhance N-to-B delivery of RNA and to explore its potential utility for …Author: Eleni Samaridou, Hannah Walgrave, Evgenia Salta, David Moreira Álvarez, Vanessa Castro-López, Mabel ...
http://jpet.aspetjournals.org/content/370/3/593
Sep 01, 2019 · This route of delivery is the subject of this review, and papers quoted are confined to publications that actually demonstrate delivery to the brain via established quantification techniques. We have also highlighted clinical studies in which nose-to-brain delivery was the intended outcome.Author: Zian Wang, Guojun Xiong, Wai Chun Tsang, Andreas G. Schätzlein, Ijeoma F. Uchegbu
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