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https://www.aiche.org/chenected/2014/02/evolution-drug-delivery
Feb 19, 2014 · The design and synthesis of drug delivery systems has evolved with the advances and innovations in science and technology. Studies of the kinetics of drug release into the body was what paved the way to the long road of exciting research, punctuated with clearer understanding and mind-blowing discoveries.
https://biospectrumasia.com/news/34/9710/evolution-of-drug-delivery-system-for-better-patient-safety.html
Oct 30, 2019 · Drug delivery systems have rapidly evolved with new technologies that support home use and can aid in patient compliance, adherence and safety. Two areas of recent innovation, in particular, are helping pharmaceutical companies meet new market demands for self-care at home: patient-controlled delivery systems and wearable injectors.
https://decisionresourcesgroup.com/blog/evolution-drug-delivery-devices-bridging-gap-medtech-pharma/
Nov 17, 2016 · Drug delivery systems have evolved over the last six decades; pills were the initial area of focus, but in the last 12 years, drugs have been delivered using self-regulated and nano-technology systems. With the markets for biosimilars and biologics surfacing, manufacturers have the opportunity to innovate and design more complex delivery methods.
https://www.sciencedirect.com/science/article/pii/S0168365908004690
It traces the evolution of the field from its origins in the 1960s to (a) the 1970s and 1980s, when numerous macroscopic “controlled” drug delivery (DD) devices and implants were designed for delivery as mucosal inserts (e.g., in the eye or vagina), as implants (e.g., sub-cutaneous or intra-muscular), as ingestible capsules (e.g., in the G-I tract), as topical patches (e.g., on the skin), and were approved for …Author: Allan S. Hoffman
https://www.nature.com/articles/s41570-017-0063
Aug 09, 2017 · Abstract Designing therapeutics is a process with many challenges. Even if the first hurdle — designing a drug that modulates the action of a particular biological target in vitro — is overcome, selective delivery to that target in vivo presents a major barrier.Author: Ashok Kakkar, Ashok Kakkar, Giovanni Traverso, Giovanni Traverso, Omid C. Farokhzad, Ralph Weisslede...
https://www.sciencedirect.com/science/article/pii/S0168365914000728
1. Introduction Implantable drug delivery systems (IDDS) originated in the 1960s when silicones were used to prolong the effectiveness of a therapy. From this beginning, the potential was recognized that this mode of delivery could overcome the problems associated with oral administration of specific therapies.Author: Lothar W. Kleiner, Jeremy C. Wright, Yunbing Wang
https://www.ondrugdelivery.com/rapid-evolution-transdermal-drug-delivery-industry-spawns-innovation/
Advanced liquid silicone rubber (LSR) and two-component injection technology can accelerate the development of transdermal drug delivery devices such as microneedle patches. There are four types of microneedles currently on the market. First is the hollow microneedle, which only requires a liquid drug formulation to be infused through the bores.
https://www.bestmedicaldegrees.com/evolution/
1930s: Drugs, electro-convulsive therapy, and surgery are used to treat people with schizophrenia and others with persistent mental illnesses. Some are infected with malaria; others are treated with repeated insulin-induced comas.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · Evolution of controlled drug delivery systems since 1950. During the 2nd generation, many other drug delivery technologies were developed. The so-called “smart” polymers and hydrogels were developed to make delivery systems that are triggered by changes in environmental factors, such as pH, temperature, or glucose.Author: Kinam Park
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