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https://www.sciencedirect.com/science/article/pii/S0958166900002020
Future directions for the commercialization of protein delivery systems. In general, protein delivery methods have continued to evolve over the past year; however, a great deal of research and development is still required to make most of these methods feasible for commercialization.Author: Jeffrey L Cleland, Ann Daugherty, Randall Mrsny
https://www.ncbi.nlm.nih.gov/pubmed/11287240
1. Curr Opin Biotechnol. 2001 Apr;12(2):212-9. Emerging protein delivery methods. Cleland JL(1), Daugherty A, Mrsny R. Author information: (1)Pharmaceutical Research & Development, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA. [email protected] The efficient and safe delivery of therapeutic proteins is the key to commercial success and, in some cases, the demonstration of ...Author: Jeffrey L Cleland, Ann Daugherty, Randall Mrsny
https://www.sciencedirect.com/science/article/abs/pii/S0958166900002020
Apr 01, 2001 · Recent advances in depot delivery systems have, for the most part, overcome all of these obstacles except for complex and costly manufacturing. On the other hand, pulmonary delivery usually involves efficient manufacturing, but low protein bioavailability resulting in …Author: Jeffrey L Cleland, Ann Daugherty, Randall Mrsny
https://www.deepdyve.com/lp/elsevier/emerging-protein-delivery-methods-05Eg35oRXI
Apr 01, 2001 · Emerging protein delivery methods Emerging protein delivery methods Cleland, Jeffrey L; Daugherty, Ann; Mrsny, Randall 2001-04-01 00:00:00 The efficient and safe delivery of therapeutic proteins is the key to commercial success and, in some cases, the demonstration of efficacy in current and future biotechnology products. Numerous delivery technologies and companies have …
https://researchportal.bath.ac.uk/en/publications/emerging-protein-delivery-methods
TY - JOUR. T1 - Emerging protein delivery methods. AU - Cleland, J L. AU - Daugherty, A. AU - Mrsny, R. PY - 2001. Y1 - 2001. M3 - Article. VL - 12. SP - 212Author: Jeffrey L Cleland, Ann Daugherty, Randall Mrsny
https://www.mdpi.com/1999-4923/11/9/441/pdf
Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods Nasir Javaid, Farzana Yasmeen and Sangdun Choi * Department of Molecular Science and Technology, Ajou University, Suwon 16499, Korea ... Various protein engineering platforms, diverse selection technologies, newAuthor: Nasir Javaid, Farzana Yasmeen, Sangdun Choi
https://link.springer.com/article/10.1007/s40259-018-0309-y
Oct 10, 2018 · Emerging delivery technologies for biotherapeutics have focused on trans-cellular pathways across the BBB utilizing receptor-mediated transcytosis (RMT). ... of various nanoparticle delivery systems using diverse materials and designs to enable more efficient gene and large protein delivery across the ... the methods used for viral expression ...Author: Danica B. Stanimirovic, Jagdeep K. Sandhu, Will J. Costain
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964012/
Jan 15, 2020 · The application of nanosuspensions in oral, ocular and pulmonary drug delivery systems have been extensively researched during the last few decades. Further, utilization of nanosuspensions in other drug delivery systems such as brain, topical, buccal, nasal and transdermal routes are under extensive investigation.Author: Shery Jacob, Anroop B. Nair, Jigar Shah
https://www.nature.com/articles/nrd4363
Aug 08, 2014 · In this Review we highlight recent advances in formulation and delivery strategies — such as the use of microsphere-based controlled-release technologies, protein modification methods that …Author: Samir Mitragotri, Paul A. Burke, Robert Langer
https://link.springer.com/article/10.2165/00063030-200519030-00003
Aug 15, 2012 · The main reasons for the low oral bioavailability of peptide drugs are pre-systemic enzymatic degradation and poor penetration of the intestinal mucosa. A considerable amount of research has focused on overcoming the challenges presented by these intestinal absorption barriers to provide effective oral delivery of peptide and protein drugs.Author: Josias H. Hamman, Gill M. Enslin, Awie F. Kotzé
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