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https://www.sciencedirect.com/science/article/pii/S0264410X05010157
Immunization to the model antigen ovalbumin was investigated using a novel intracutaneous delivery system consisting of antigen-coated microneedle arrays. The influence of the following parameters on the resulting immune responses was investigated: depth of vaccine delivery, dose of vaccine delivered, density of microneedles on the array, and ...Author: Georg Widera, Juanita Johnson, Lomi Kim, Luz Libiran, Kofi Nyam, Peter E. Daddona, Michel Cormier
https://www.ncbi.nlm.nih.gov/pubmed/16246466
Mar 06, 2006 · Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system. Widera G(1), Johnson J, Kim L, Libiran L, Nyam K, Daddona PE, Cormier M. Author information: (1)ALZA Corporation, Physiological Systems, 1900 Charleston Road, Mountain View, CA 94039-7210, USA.Author: Georg Widera, Juanita Johnson, Lomi Kim, Luz Libiran, Kofi Nyam, Peter E. Daddona, Michel Cormier
https://www.researchgate.net/publication/7521151_Effect_of_delivery_parameters_on_immunization_to_ovalbumin_following_intracutaneous_administration_by_a_coated_microneedle_array_patch_system
Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system Article in Vaccine 24(10):1653-64 · April 2006 with ...
https://www.sciencedirect.com/science/article/pii/S0928098714003133
Parameter optimization toward optimal microneedle-based dermal vaccination ... or radioactively labeled) ovalbumin. Next, these different microneedles and several factors, including the dose of ovalbumin, the effect of using an ... K. Nyam, P.E. Daddona, M. CormierEffect of delivery parameters on immunization to ovalbumin following ...Author: Koen van der Maaden, Eleni Maria Varypataki, Huixin Yu, Stefan Romeijn, Wim Jiskoot, Joke Bouwstra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066337/
Mar 03, 2011 · Enhancement of transdermal delivery of peptides due to incorporation of penetration enhancers, addition of facilitating peptide sequences, chemical modification of the peptide itself or encapsulation, is limited to only a narrow range of small peptides. Therefore, different enhancement methods need to be employed for larger proteins.Author: Haripriya Kalluri, Ajay K. Banga
https://www.zosanopharma.com/technology/publications/
Effect of delivery parameters on immunization to ovalbumin following intracutaneous administration by a coated microneedle array patch system Georg Widera, Juanita Johnson, Lomi Kim, Luz Libiran, Kofi Nyam, Peter E. Daddona, Michel Cormier. Vaccine 24, 1653-1664, 2006. Transdermal delivery of desmopressin using a coated microneedle array patch ...
https://www.researchgate.net/publication/325415975_Development_of_PLGA_nanoparticle_loaded_dissolving_microneedles_and_comparison_with_hollow_microneedles_in_intradermal_vaccine_delivery
The delivery system of vaccines has been advanced along with time as well. New delivery systems such as nanoparticles, liposomes, or cells (for DNA) has been proven to develop a more efficient ...
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0220382
The microneedle patch has been shown to be an effective delivery technology, allowing for efficient vaccination and facile antigen delivery to the skin [1,26]. Immunization based on the antigen ovalbumin (OVA) model was studied using a novel transcutaneous delivery system consisting of an antigen-coated microneedle patch [1,5,27].Author: Sung-Ju Lee, Hyeon-Seong Lee, Yun-Ho Hwang, Jong-Jin Kim, Kyung-Yun Kang, Seong Jin Kim, Hong Kee Ki...
https://link.springer.com/article/10.1186/1710-1492-10-47
Maternal immunization with ovalbumin or Dermatophagoides pteronyssinus has opposing effects on ... the effect of maternal immunization with Dp on the expression of inhibitory receptors in offspring B cells has not been evaluated. ... Taylor GW, Garrod DR, Cannell MB, Robinson C: Der p 1 facilitates transepithelial allergen delivery by ...Author: Aline Aparecida de Lima Lira, Marília Garcia de Oliveira, Luana Mendonça de Oliveira, Alberto José d...
https://www.nature.com/articles/gt201022
Coated microneedles have been used previously to vaccinate mice with inactivated influenza virus and guinea pigs with ovalbumin. 5, 6. ... Effect of delivery parameters on immunization to ...Author: Harvinder S. Gill, Harvinder S. Gill, Jonas Sõderholm, Jonas Sõderholm, Mark R. Prausnitz, Matti Säl...
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