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https://www2.ts.ctw.utwente.nl/frans/expert%20opinion%20on%20drug%20delivery%20frijlink%20and%20de%20boer.pdf
The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery. However ...Author: H.W. Frijlink, A.H. De Boer
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
For decades pulmonary drug delivery, either via pressurised metered-dose inhalers (pMDIs) or dry powder inhalers (DPIs), has been used in the topical treatment of respiratory tract diseases such as asthma (Islam and Cleary, 2012; Islam and Gladki, 2008). Yet, with advances in nanotechnology and the development of aerosol drug formulations ...
https://www.sciencedirect.com/topics/medicine-and-dentistry/dry-powder-inhaler
Yousef Javadzadeh, Shadi Yaqoubi, in Nanostructures for Drug Delivery, 2017. 6.3 Dry Powder Inhaler. Dry powder inhalers (DPI) are the third type of inhaler device that seems to be the most promising devices for future use (Hamishehkar et al., 2012).The breath actuating possibility of these devices is an advanced feature that overcomes the problem of coordination of patient breathing and the ...
https://www.ncbi.nlm.nih.gov/pubmed/16296721
The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery.Author: H.W. Frijlink, A.H. De Boer
https://www.pharmaexcipients.com/news/dry-powder-inhaler-for-pulmonary-drug-delivery/
Oct 17, 2017 · Pulmonary drug delivery is the promising delivery route to treat not only respiratory diseases but also systemic diseases and has proven as a potential delivery route for complex drugs that cannot be delivered orally. Development of dry powder inhalation systems targets the delivery of fine drug particles to the deep lung surface by a ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884297/
Apr 18, 2002 · Pulmonary delivery devices. The lung has served as a route of drug administration for thousands of years. The origin of inhaled therapies can be traced back 4000 years ago to India, where people smoked the leaves of the Atropa belladonna plant to suppress cough. In the 19th and early 20th centuries, asthmatics smoked asthma cigarettes that contained stramonium powder mixed with …Author: N. R. Labiris, M. B. Dolovich
https://www.researchgate.net/publication/7471346_Dry_powder_inhalers_for_pulmonary_drug_delivery
Dry powder inhalers for pulmonary drug delivery Article · Literature Review (PDF Available) in Expert Opinion on Drug Delivery 1(1):67-86 · December 2004 with 2,381 Reads How we measure 'reads'
https://link.springer.com/article/10.1007/s40005-017-0359-z
Oct 12, 2017 · Pulmonary drug delivery is the promising delivery route to treat not only respiratory diseases but also systemic diseases and has proven as a potential delivery route for complex drugs that cannot be delivered orally. Development of dry powder inhalation systems targets the delivery of fine drug particles to the deep lung surface by a combination of particle deposition and clearance in human ...Author: Hong-Goo Lee, Dong-Wook Kim, Chung-Woong Park
https://www.ondrugdelivery.com/overview-dry-powder-inhalation-systemic-drug-delivery/
By this point, devices for delivery via the pulmonary route had already been developed: nebulisers, metered dose inhalers (MDIs) and dry powder inhalers (DPIs). 3,4 The former two use various solvents, both aqueous and organic, thus meaning DPIs offer the best prospect for developing a stable system. Devices for inhalation therapy must be able ...
https://www.tandfonline.com/doi/abs/10.1517/17425247.1.1.67
Apr 03, 2018 · The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery.Author: H.W. Frijlink, A.H. De Boer
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