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https://www2.ts.ctw.utwente.nl/frans/expert%20opinion%20on%20drug%20delivery%20frijlink%20and%20de%20boer.pdf
and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery. However, they are also complicated systems, the the performance of which relies on many aspects, including the design of the inhaler (e.g., resistance to …Author: H.W. Frijlink, A.H. De Boer
https://www.ncbi.nlm.nih.gov/pubmed/16296721
Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery. However, they are also complicated systems, the the performance of which relies on many aspects, including the design of the inhaler (e.g., resistance to air flow and the used de-agglomeration principle to generate the inhalation aerosol), the powder formulation and the air flow generated by the patient.Author: H.W. Frijlink, A.H. De Boer
https://www.tandfonline.com/doi/abs/10.1517/17425247.1.1.67
Apr 03, 2018 · The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery.Author: H.W. Frijlink, A.H. De Boer
https://www.academia.edu/15642146/Dry_powder_inhalers_for_pulmonary_drug_delivery
Dry powder inhalers for pulmonary drug delivery
https://www.researchgate.net/publication/7471346_Dry_powder_inhalers_for_pulmonary_drug_delivery
The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery.
https://www.tandfonline.com/doi/abs/10.1080/17425247.2016.1224846?needAccess=true
Introduction: Early dry powder inhalers (DPIs) were designed for low drug doses in asthma and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked efficient dispersion ...
https://manufacturingchemist.com/news/article_page/A_novel_platform_for_DP_inhalation_drugs/65444
Novel dry powder delivery technologies have tremendous potential to enhance existing drugs and enable innovative products, particularly if these new delivery platforms can meet the needs of next generation inhaled drugs while overcoming the shortcomings of current approaches. Pulmatrix describes a novel inhaled dry powder (DP) delivery platform termed iSPERSE (inhaled small particles easily ...
https://www.altmetric.com/details/10993282
Improved inhaler design is desired to make dry powder inhalation for future applications cost-effective and safe. With an increasing interest in high dose drug delivery, vaccination and systemic delivery via the respiratory tract, innovative formulation technologies alone may not be sufficient.
https://www.sciencedirect.com/topics/medicine-and-dentistry/dry-powder-inhaler
A dry powder inhaler (DPI) is a breath-actuated device that delivers the drug in the form of particles contained in a capsule or blister that is punctured prior to use. This type of inhaler requires an adequate inspiratory flow rate for drug delivery, as it does not include a propellant (Harris, 2008).
http://www.americanpharmaceuticalreview.com/Featured-Articles/337338-Defining-the-Dose-for-Dry-Powder-Inhalers-The-Challenge-of-Correlating-In-Vitro-Dose-Delivery-Results-with-Clinical-Efficacy/
Apr 30, 2017 · The lung is an established route for the delivery of drugs to patients with a wide range of inhaled products being available to treat respiratory conditions such as asthma, chronic obstructive pulmonary disease, and cystic fibrosis.
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