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https://www.researchgate.net/publication/5564013_Drug_Release_Kinetics_From_Stent_Device-Based_Delivery_Systems
Drug Release Kinetics From Stent Device-Based Delivery Systems Article · Literature Review in Journal of Cardiovascular Pharmacology 51(2):118-25 · March 2008 with 23 Reads How we measure 'reads'
https://journals.lww.com/cardiovascularpharm/Fulltext/2008/02000/Drug_Release_Kinetics_From_Stent_Device_Based.2.aspx
Thus, a detailed understanding of drug release kinetics is necessary for rational design of stent-based drug delivery systems to optimize therapeutic efficacy and minimize local vascular toxicity. DRUG-ELUTING STENT. A drug-eluting stent consists of 3 main components: the stent platform, the active pharmacologic agents, and a carrier vehicle.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846103/
Mathematical modeling of drug release kinetics provides a basis for the study of mass transport mechanisms that are involved in the control of drug release . There have been several nicely written reviews on mathematical modeling for bioerodible polymeric delivery systems , dissolution controlled drug delivery systems , microsphere delivery ...Author: Yao Fu, Weiyuan John Kao
https://journals.lww.com/cardiovascularpharm/Pages/articleviewer.aspx?year=2008&issue=02000&article=00002&type=Fulltext
the systemic circulation and other organs. The drug carrier matrix allows the release of the drug in a diffusion-controlled manner over an extended time period after the stent implant. The drugs are chosen such that the complex cascade of events that occurs after stent implantation that leads to smooth muscle cell proliferation and migration towards the intima are inhibited. The success of an ...
https://insights.ovid.com/cardiovascular-pharmacology/jcph/2008/02/000/drug-release-kinetics-stent-device-based-delivery/2/00005344
This review highlights the various factors involved in drug release kinetics, local vascular toxicity, carrier vehicle matrix, tissue deposition, and distribution through the …Author: Belay Tesfamariam
https://asmedigitalcollection.asme.org/medicaldevices/article/7/1/011005/376504/Development-and-Evaluation-of-Drug-Eluting-Stent
Drug Release Kinetics From Stent Device-Based Delivery Systems,” J. Cardiovasc. Pharmacol. ... Chitosan-Based Drug Delivery Systems. Chitosan and Its Derivatives as Promising Drug Delivery Carriers. Synthesis and Characterization of Carboxymethyl Chitosan Based Hybrid Biopolymer Scaffold.Author: Ashok Thakkar, Ankur Raval, Ramila Mandal, Sanjay Parmar, Arpit Jariwala, Jaynish Tailor, Anita Meht...
https://www.researchgate.net/publication/6629603_Local_vascular_toxicokinetics_of_stent-based_drug_delivery
Local vascular toxicokinetics of stent-based drug delivery Article in Toxicology Letters 168(2):93-102 · February 2007 with 6 Reads How we measure 'reads'
https://link.springer.com/article/10.1007/s11095-008-9721-1
Sep 09, 2008 · The amorphous form of a drug may provide enhanced solubility, dissolution rate, and bioavailability but will also potentially crystallize over time. Miscible polymeric additives provide a means to increase physical stability. Understanding the miscibility of drug–polymer systems is of interest to optimize the formulation of such systems. The purpose of this work was to develop experimental ...Author: Patrick J. Marsac, Patrick J. Marsac, Tonglei Li, Lynne S. Taylor
https://onlinelibrary.wiley.com/doi/10.1002/jbm.a.30188
The polymer carrier technology in the TAXUS™ drug‐eluting stent consists of a thermoplastic elastomer poly(styrene‐b‐isobutylene‐b‐styrene) (SIBS) with ...Author: Shrirang V. Ranade, Kathleen M. Miller, Robert E. Richard, A. Ken Chan, Michael J. Allen, Michael N....
https://www.sciencedirect.com/science/article/pii/S0928098709000414
Based on the obtained knowledge, the selection of an appropriate release medium for in vitro tests of the drug delivery systems can be facilitated, and an accelerated in vitro release method can be developed allowing for a rapid feedback on the release characteristics of a specific polymeric formulation. ... B. TesfamariamDrug release kinetics ...Author: Marika Kamberi, Sushma Nayak, Kathy Myo-Min, Troy P. Carter, Leonard Hancock, Debra Feder
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