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https://erj.ersjournals.com/content/erj/44/3/765.full.pdf
The lung is a unique organ for drug delivery. Its large surface area, thin epithelium layer and rich blood supply ensure fast drug absorption. These properties offer not only the possibility to treat lung disease, but also allow for the systemic application of drugs. Levels of metabolism in …Author: Sabine H. van Rijt, Thomas Bein, Silke Meiners
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
Hence, better understanding of these parameters and their interrelationship will help us to maximize the efficiency and benefits of pulmonary drug delivery system. Lung as an important organ, major contribution of research in this area may help to achieve safer pulmonary …
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is becoming increasingly used. When developing pulmonary drugs, pharmaceutical chemists must consider drug absorption, control of particle size, suitable toxicology models, and patient compliance. The author reviews the issues specific to developing drugs designed for pulmonary delivery and considers how—with the right knowledge and expertise—these challenges …
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
Pulmonary drug delivery is getting more and more magnitude. This is on account of the specific physiological environment of the lung as an absorption and treatment organ. The development of inhalable insulin can be perceived as a milestone in pulmonary drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884307/
Apr 19, 2002 · Part I of this review on pulmonary drug delivery addresses the physiological factors affecting therapeutic effectiveness of inhaled drug therapy, including aerosol particle size, airway geometry, lung clearance mechanisms, and lung disease.Author: N. R. Labiris, M. B. Dolovich
https://erj.ersjournals.com/content/44/3/765
Sep 01, 2014 · In asthma, for example, drug delivery to the upper airways is needed while for alveolar lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis, it is important to have drug deposition in the deep lung rather than the upper airways.Author: Sabine H. van Rijt, Thomas Bein, Silke Meiners
https://www.amazon.com/Drug-Delivery-Biology-Health-Disease/dp/0824705416
Drug Delivery to the Lung (Lung Biology in Health and Disease): 9780824705411: Medicine & Health Science Books @ Amazon.comAuthor: Hans Bisgaard
https://www.sciencedirect.com/science/article/pii/B9780128157206000101
1. An Overview of Pulmonary Drug Delivery in Lung Cancer Therapy 1.1. Main Advantages. Compared to systemic delivery, aerosol chemotherapy could potentially lead to three main benefits for lung cancer therapy .First, the use of the inhalation route for lung diseases represents a …Author: Rémi Rosiere, Karim Amighi, Nathalie Wauthoz
http://www.worldpharmaceuticals.net/contractors/drug-delivery-systems/nektar-therapeutics/
Pharmaceutical companies and drug delivery companies are also focused on developing pulmonary delivery systems to treat local lung diseases, and to deliver drugs for conditions where fast onset is desirable, such as pain relief, allergic reactions and sexual dysfunction.
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