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https://www.mdpi.com/1996-1944/3/3/1928/pdf
Indeed, targeted delivery can be much more efficient than systemic application, while improving bioavailability and limiting undesirable side effects. This review describes how the use of targeted nanocarriers such as nanoparticles and liposomes can improve the pharmacokinetic properties of protein drugs, thus increasing their safety and maximizingAuthor: Roberto Solaro, Federica Chiellini, Antonella Battisti
https://www.researchgate.net/publication/42539473_Targeted_Delivery_of_Protein_Drugs_by_Nanocarriers
This review describes how the use of targeted nanocarriers such as nanoparticles and liposomes can improve the pharmacokinetic properties of protein drugs, thus increasing their safety and ...
https://www.ncbi.nlm.nih.gov/pubmed/26061298
Nanocarriers for cancer-targeted drug delivery. ... In addition to improving the pharmacokinetics of the loaded poorly soluble hydrophobic drugs by solubilizing them in the hydrophobic compartments, nanoparticles allowed cancer specific drug delivery by inherent passive targeting phenomena and adopted active targeting strategies. For this ...Author: Preeti Kumari, Balaram Ghosh, Swati Biswas
https://www.mdpi.com/1996-1944/3/3/1928/htm
Recent advances in biotechnology demonstrate that peptides and proteins are the basis of a new generation of drugs. However, the transportation of protein drugs in the body is limited by their high molecular weight, which prevents the crossing of tissue barriers, and by their short lifetime due to immuno response and enzymatic degradation.Author: Roberto Solaro, Federica Chiellini, Antonella Battisti
https://www.sciencedirect.com/book/9780128140338/nanocarriers-for-drug-delivery
This chapter describes how proteins can be used to provide effective targeted nanocarriers for drugs to target tumors. This approach offers an exciting framework for cancer therapies in the future, allowing multiple therapeutic agents and other functions to be combined in the same particle and ensuring a lower toxicity for the patient.
https://www.sciencedirect.com/science/article/pii/B9780128140338000060
6. Protein and Hybrid Protein Nanocarriers in Targeted Drug Delivery. NP-based delivery of therapeutic proteins and genes is believed to be a significant area of drug delivery. For delivery of therapeutic proteins or drugs, a number of protein–NP-based delivery systems are being used, such as albumin, gelatin, and legumin . The incorporation ...Author: Mahadevappa Y. Kariduraganavar, Geetha B. Heggannavar, Sandra Amado, Geoffrey R. Mitchell, Geoffrey ...
http://europepmc.org/articles/PMC5445892
Mar 01, 2010 · None of the reported nanocarriers can be considered the best choice for all potential applications. At present, however, polymeric nanoparticles seem to be the most versatile carrier for the targeted delivery of protein drugs.Author: Roberto Solaro, Federica Chiellini, Antonella Battisti
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743941/
One of the main goals of nanomedicine is to develop a nanocarrier that can selectively deliver anti-cancer drugs to the targeted tumors. Extensive efforts have resulted in several tumor-targeted nanocarriers, some of which are approved for clinical use.
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