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https://stm.sciencemag.org/content/4/130/130ra48.full
Apr 18, 2012 · Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2 + Breast Cancer Growth and Metastasis. By Yan-dan Yao, Tian-meng Sun, Song-yin Huang, Shuang Dou, Ling Lin, Jia-ning Chen, Jian-bin Ruan, Cheng-qiong Mao, Feng-yan Yu, Mu-sheng Zeng, Jian-ye Zang, Qiang Liu, Feng-xi Su, Peter Zhang, Judy Lieberman, Jun Wang, Erwei Song.Author: Yan-dan Yao, Tian-meng Sun, Song-yin Huang, Shuang Dou, Ling Lin, Jia-ning Chen, Jian-bin Ruan, Chen...
https://www.researchgate.net/publication/224770279_Targeted_Delivery_of_PLK1-siRNA_by_ScFv_Suppresses_Her2_Breast_Cancer_Growth_and_Metastasis
Apr 18, 2012 · Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2. ... breast cancer growth and metastasis in vitro. and in vivo by inducing cell cycle arre st and apoptosis, without triggering.
https://stm.sciencemag.org/content/scitransmed/4/130/130ra48.full.pdf
BREAST CANCER Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis Yan-dan Yao,1* Tian-meng Sun,2* Song-yin Huang,1 Shuang Dou,2 Ling Lin,1 Jia-ning Chen,1 Jian-bin Ruan,2 Cheng-qiong Mao,2 Feng-yan Yu,1 Mu-sheng Zeng,3 Jian-ye Zang,2 Qiang Liu,1 Feng-xi Su,1 Peter Zhang,4 Judy Lieberman,5† Jun Wang,2† Erwei Song1† A major obstacle to …Author: Yan-dan Yao, Tian-meng Sun, Song-yin Huang, Shuang Dou, Ling Lin, Jia-ning Chen, Jian-bin Ruan, Chen...
https://www.ncbi.nlm.nih.gov/pubmed/22517885
Moved Permanently. The document has moved here.Author: Yan-dan Yao, Tian-meng Sun, Song-yin Huang, Shuang Dou, Ling Lin, Jia-ning Chen, Jian-bin Ruan, Chen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445934/
Targeted treatment of metastatic breast cancer by PLK1 siRNA delivered by an antioxidant nanoparticle platform. ... Targeted delivery of siRNAs by nanoparticles holds great promise for cancer treatment since siRNA can target any gene deemed important to cancer progression, metastasis, and drug resistance with high specificity .Author: Jingga Morry, Worapol Ngamcherdtrakul, Shenda Gu, Moataz Reda, David J. Castro, Thanapon Sangvanich,...
https://mct.aacrjournals.org/content/molcanther/16/4/763.full.pdf
Models and Technologies Targeted Treatment of Metastatic Breast Cancer by PLK1 siRNA Delivered by an Antioxidant Nanoparticle Platform Jingga Morry1,Worapol Ngamcherdtrakul1,2, Shenda Gu1, Moataz Reda1, David J. Castro1,2,Thanapon Sangvanich1, Joe W. Gray1, and Wassana Yantasee1,2 AbstractAuthor: Jingga Morry, Worapol Ngamcherdtrakul, Shenda Gu, Moataz Reda, David J. Castro, Thanapon Sangvanich,...
https://mct.aacrjournals.org/content/16/4/763
Apr 01, 2017 · Metastatic breast cancer is developed in about 20% to 30% of newly diagnosed patients with early-stage breast cancer despite treatments. Herein, we report a novel nanoparticle platform with intrinsic antimetastatic properties for the targeted delivery of Polo-like kinase 1 siRNA (siPLK1). We first evaluated it in a triple-negative breast cancer (TNBC) model, which shows high metastatic ...Author: Jingga Morry, Worapol Ngamcherdtrakul, Shenda Gu, Moataz Reda, David J. Castro, Thanapon Sangvanich,...
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