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http://www.authorstream.com/Presentation/priyadebnath-1542656-ocular-drug-delivery-system/
Sep 17, 2012 · INTRODUCTION Ocular administration of drug is primarily associated with the need to treat ophthalmic diseases. Eye is the most easily accessible site for topical administration of a medication. Ideal ophthalmic drug delivery must be able to sustain the drug release and to remain in the vicinity of front of the eye for prolong period of time.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
Concentration of drug available in the precorneal area acts as a driving force for its passive diffusion across cornea. However, for efficient ocular drug delivery with eye drops, high corneal permeation with longer drug cornea contact time is required. Several efforts have been made toward improving precorneal residence time and corneal ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Ocular Drug Delivery AswAni Dutt VADlApuDi, Kishore CholKAr, supriyA reDDy DAsAri, AnD Ashim K. mitrA CHAPTER OBJECTIVES Upon completing this chapter, the reader should be able to Describe the anatomy and physiology of the eye. Understand the importance of various routes of drug administration to the eye. Describe various barriers to ocular drug delivery and constraints with
http://www.authorstream.com/Presentation/guru123456789-1388210-ocular-drug-delivery-system/
Apr 13, 2012 · Ocular drug delivery system (ODDS): Ocular drug delivery system (ODDS) 3 Introduction Objectives of ODDS 1. In the treatment of local and systemic ophthalmic diseases 2. To design a therapeutic system to achieve an optimal drug concentration at the …
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug delivery to the eye is a complex process. As a self-contained system, the eye is unique in the body in many ways that affect pharmacology and toxicology. It includes several different cell types, and functions as a complete, self-contained system. The rate and efficacy of …
https://www.slideshare.net/RikeshlalShrestha/ocular-drug-delivery-system-ppt
Apr 04, 2017 · Biopharmaceutics - Ocular Drug Delivery System ... Ocular drug delivery system ppt 1. ... Spillage of drug by overflow: • Eye can accommodate 30 L without blinking. • Eye dropper deliver volume of 50 L, 70% of administered dose is expelled by over flow. • Upon Blinking 10 L residual volume is left (i.e 90% of the dose expelled) b ...
https://www.slideshare.net/pharmD_maha/ocular-drug-delivery-system-48322893
May 19, 2015 · 1. Ocular Drug Delivery System Dr.Samar Alshawaa, Dr.Etdal Fouda. Presented by: Maha Al-Khalifah, Majd Al-Sarhani and Reem Al-Saif. Basic Principles of Pharmaceutical Sciences. (PHS 201 M) 2. Table of Contents Introduction Structure of the eye. Eye layers. Lacrimal apparatus. Composition of the the eye. Mechanism of Drug Absorption.
https://www.glaucoma.org/treatment/alternative-drug-delivery-systems-for-glaucoma.php
Much work needs to be done before we know exactly how well these new drug delivery options will perform. But it is gratifying to know that new and better ways to treat glaucoma are on the way. Hopefully, this kind of alternative drug delivery technology will result in …
https://eye.hms.harvard.edu/topic/drug-delivery-medical-devices
We hypothesized that a drug-eluting contact lens that rests on the cornea would therefore be well-suited for delivering drugs to the eye including the retina. We developed a contact lens based dexamethasone delivery system (Dex-DS) that achieved sustained drug delivery to the retina at therapeutic levels.
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