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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
The major challenge faced by today’s pharmacologist and formulation scientist is ocular drug delivery. Topical eye drop is the most convenient and patient compliant route of drug administration, especially for the treatment of anterior segment diseases.Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://eye.hms.harvard.edu/topic/drug-delivery-medical-devices
We hypothesized that a drug-eluting contact lens that rests on the cornea would therefore be well-suited for delivering drugs to the eye including the retina. We developed a contact lens based dexamethasone delivery system (Dex-DS) that achieved sustained drug delivery to the retina at therapeutic levels.
iVeena develops ocular drug products that eliminate the need to apply eye drops and painful injections. iVeena also develops implants that deliver drugs more efficiently to the front and back of the eye.
https://www.healio.com/ophthalmology/cornea-external-disease/news/print/ocular-surgery-news/%7Bd69fee03-15c5-4fbd-a090-4f8a5b294c17%7D/understanding-topical-ophthalmic-drug-delivery-how-much-gets-in
Ocular Surgery News In understanding how much of an artificial tear or a prescription eye drop actually reaches its target tissue, it is helpful to appreciate the significant obstacles to drug ...
https://pharm.ucsf.edu/desai/research/ocular-drug-delivery
Ocular Drug Delivery. Ocular diseases affect one of the most indispensable senses and cause significant impacts to quality of life, particularly in the elderly. The delicate structures of the eye require particular care when developing novel therapies. Topical eye drops and intraocular injections are two methods that have been employed for ...
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug delivery to the eye is a complex process. As a self-contained system, the eye is unique in the body in many ways that affect pharmacology and toxicology. It includes several different cell types, and functions as a complete, self-contained system. The rate and efficacy of …
https://www.sciencedirect.com/science/article/pii/S0753332218306863
Major proportion of market of ophthalmic products is occupied by topical formulations which includes eye drops (major), eye ointments, contact lens, cul-de-sac inserts, punctual plugs etc. Being the most convenient and efficacious non-invasive route, it is the most preferred especially for drug delivery to anterior segment.Author: Kritika Nayak, Manju Misra
https://futurism.com/neoscope/device-treats-illness-inside-eye
A new drug delivery device implanted in a patient's eye gradually releases anti-glaucoma drugs over the course of six months, until it completely dissolves.
https://www.ondrugdelivery.com/advanced-drug-delivery-for-dry-eye-treatment/
Citation: Kraus R, Woesthuis W, “Advanced Drug Delivery for Dry Eye Treatment”. ONdrugDelivery Magazine, Issue 104 (Jan 2020), pp 4-6. Rouven Kraus and Wilfried Woesthuis discuss Aero Pump and Medspray’s new open-eye spray for the treatment of dry eyes.
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