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https://reference.medscape.com/medline/abstract/20036827
In this setting, the possible use of drug delivery systems (DDS) loaded with antibiotics that exhibit a high in vitro bactericidal activity deserves to be considered. Entrapping or encapsulating the drug within a delivery system provides a greater control of the pharmacokinetic behavior of the active molecule.
https://www.researchgate.net/publication/40785581_Drug_delivery_systems_for_potential_treatment_of_intracellular_bacterial_infections
Drug delivery systems for potential treatment of intracellular bacterial infections Article · Literature Review (PDF Available) in Frontiers in Bioscience 15(2):397-417 · January 2010 with 711 Reads
https://dadun.unav.edu/handle/10171/22391
Drug delivery systems for potential treatment of intracellular bacterial infections. Front Biosci 2010 Jan 1;15:397-417. Resumen . Despite the advent of a considerable number of new antibiotics, treatment of intracellular pathogens still represents a major pharmaceutical challenge. The antibiotic concentration in those specialized niches are ...Author: E. Imbuluzqueta, C. Gamazo, J. Ariza, M.J. Blanco-Prieto
https://www.sciencedirect.com/science/article/pii/S0924857914000648
In this review, we will discuss the more relevant advances in the field of antibiotic delivery for the treatment of intracellular bacterial infections, mainly those occurring in phagocytic cells. 4. Liposomes. The best known and most widely investigated platform for drug transportation is the liposome.Author: Nadia Abed, Patrick Couvreur
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197093/
1. Introduction. Despite the profound success achieved by the use of antibiotics against infectious diseases, bacterial infections continue to impose significant challenges on global healthcare 1, 2.Eradication of certain bacterial infections such as tuberculosis remains difficult due to the complex mechanisms of the pathogen in subverting its host’s immune system as well as the delivery ...Author: Weiwei Gao, Soracha Thamphiwatana, Pavimol Angsantikul, Liangfang Zhang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628058/
Apr 11, 2019 · The nanoparticulate drug delivery approach for intracellular infections mimics the endocytic or phagocytic pathway of pathogens to localize within the host cells . Nanotechnology offers unprecedented opportunities for intracellular drug delivery by engineering nanoparticles with various composition and surface functionalization .
https://www.sciencedirect.com/science/article/pii/S1931524420300463
The site of infection and the length of treatment are factors that can influence the design of drug delivery platforms for bacterial infections. Accordingly, formulations can range from being multidose depots to drug-loaded particulate systems that can protect the cargo …
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/nanoparticle-based-drug-delivery-systems-for-treatment-of-infectious-diseases
With the continuous attempts in this field, there is no doubt that nanoparticle-based drug delivery systems will continue to improve treatment to bacterial infections, particularly in life-threatening diseases such as tuberculosis infections.Author: Mojtaba Salouti, Azam Ahangari
https://dadun.unav.edu/bitstream/10171/22391/1/1092%20revised.pdf
Drug delivery systems for potential treatment of intracellular bacterial infections Edurne Imbuluzqueta1, Carlos Gamazo2, Javier Ariza3, Maria J. Blanco-Prieto1 1Department of Pharmacy and Pharmaceutical Technology, University of Navarra, 31080 Pamplona, Spain, 2Department of Microbiology and Parasitology, University of Navarra, 31080 Pamplona, Spain, 3Infectious Disease Service, HospitalAuthor: E. Imbuluzqueta, C. Gamazo, J. Ariza, M.J. Blanco-Prieto
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