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https://link.springer.com/article/10.1007/s11095-012-0959-2
Jan 10, 2013 · Combined with new drugs, drug delivery systems will eventually provide useful treatments for ischemic stroke. Stroke is the third leading cause of death in the United States. Reduced cerebral blood flow causes acute damage to the brain due to excitotoxicity, reactiAuthor: Taiyoun Rhim, Dong Yun Lee, Minhyung Lee
https://www.researchgate.net/publication/234105426_Drug_Delivery_Systems_for_the_Treatment_of_Ischemic_Stroke
In clinical settings, tissue plasminogen activator (t-PA) for thrombolytic therapy is the only globally approved drug for the treatment of ischemic stroke.
https://www.deepdyve.com/lp/springer-journals/drug-delivery-systems-for-the-treatment-of-ischemic-stroke-gANvYkcskz
Jan 10, 2013 · Drug Delivery Systems for the Treatment of Ischemic Stroke Drug Delivery Systems for the Treatment of Ischemic Stroke Rhim, Taiyoun; Lee, Dong; Lee, Minhyung 2013-01-10 00:00:00 Stroke is the third leading cause of death in the United States. Reduced cerebral blood flow causes acute damage to the brain due to excitotoxicity, reactive oxygen species (ROS), and ischemia.
http://www.eurekaselect.com/146691/article
However, the only FDA approved treatment for ischemic strokes is tissue plasminogen activator, and no effective targeted therapy for hemorrhagic stroke exists yet. Methods: The goal of this work is to review the brain drug delivery systems (BDDS) used for stroke intervention and recovery.Author: Tiantian Luo, Ju Wang, Shilei Hao, Tingwang Guo, Peng Ren, Zhongjun Cheng, Feiyan Gao, Yuhua Gong, B...
https://www.jstage.jst.go.jp/article/bpb/42/3/42_b18-00683/_html/-char/en
Ischemic stroke is one of the leading causes of severe disability and death. In clinical settings, tissue plasminogen activator (t-PA) for thrombolytic therapy is the only globally approved drug for the treatment of ischemic stroke.Author: Tatsuya Fukuta, Tatsuya Fukuta, Takayuki Ishii, Tomohiro Asai, Naoto Oku, Naoto Oku
https://www.sciencedirect.com/science/article/pii/B9780128139974000244
Stroke treatment strategies include early revascularization through delivery of thrombolytics to recanalize intracranial vessels and delivery of therapeutics for neuroprotection. CNS drug delivery is complicated by the blood–brain barrier and by the functional changes that occur after acute stroke, which can prevent CNS localization.Author: Nguyen Hoang, Shahid M. Nimjee
https://www.nature.com/articles/srep12651
Jul 29, 2015 · The enhanced accumulation of T7-P-LPs in brain encouraged us to use it as a targeting drug delivery system for ZL006 to treat ischemic stroke.Author: Zhongyuan Wang, Yue Zhao, Yan Jiang, Wei Lv, Lin Wu, Baoyan Wang, Lingyan Lv, Qunwei Xu, Hongliang X...
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