Drug Delivery Endothel

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Intraluminal Drug Delivery to the Mouse Arteriovenous ...

    https://www.jove.com/video/53905/intraluminal-drug-delivery-to-mouse-arteriovenous-fistula
    In this report, intraluminal drug delivery with simultaneous AVF creation in mice is described, using a suture-less model of AVF creation. By using this modified murine AVF model a simple method for intraluminal drug delivery to the venous limb of the fistula can be performed.

(PDF) Nanoparticles and endothelium: An update on the ...

    https://www.researchgate.net/publication/287311226_Nanoparticles_and_endothelium_An_update_on_the_toxicological_interactions
    A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.

(PDF) Nanoparticles and microparticles for skin drug delivery

    https://www.researchgate.net/publication/49830276_Nanoparticles_and_microparticles_for_skin_drug_delivery
    Nanoparticles and microparticles for skin drug delivery Article · Literature Review (PDF Available) in Advanced drug delivery reviews 63(6):470-91 · February 2011 with 4,679 Reads

Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific ...

    https://www.sciencedirect.com/science/article/pii/S0168365913009711
    Until now drug delivery based selective NFκB interference with activated endothelium has been demonstrated using only adenoviral gene therapy , , whereas only a few non-viral carriers are currently available for in vivo siRNA delivery into endothelial cells , .Author: Piotr S. Kowalski, Peter J. Zwiers, Henriëtte W.M. Morselt, Joanna M. Kuldo, Niek G.J. Leus, Marcel ...

Endothelium - Wikipedia

    https://en.wikipedia.org/wiki/Endothelium
    Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. It is a thin layer of simple, or single-layered, squamous cells called endothelial cells.Endothelial cells in direct contact with blood are called vascular endothelial cells, whereas those in ...

Endothelial Function Testing Cedars-Sinai

    https://www.cedars-sinai.org/programs/heart/clinical/womens-heart/services/endothelial-function-testing.html
    Endothelial Function Testing The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction as well as enzymes that control blood clotting, immune function and platelet (a colorless substance in the blood) adhesion.

Paclitaxel’s Mechanistic and Clinical Effects on Breast Cancer

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995578/
    Nov 27, 2019 · Paclitaxel (PTX), a class of taxanes, is an antineoplastic drug with an impact on the stabilization of microtubules, which represents a widely used chemotherapeutic agent in numerous cancers. The effect of PTX as an antimitotic drug was documented in a large number of studies [6,7,8]. Moreover, the mechanisms of PTX action associated with the ...Author: Tala M. Abu Samaan, Marek Samec, Alena Liskova, Peter Kubatka, Dietrich Büsselberg

Context-dependent functions of angiopoietin 2 are ...

    https://www.pnas.org/content/115/6/1298
    Feb 06, 2018 · Reducing vascular leakage and stabilizing the endothelium through activation of the angiopoietin (ANGPT)–TIE2 receptor tyrosine kinase pathway is a promising therapeutic strategy for vascular diseases. ANGPT2 is one of two major ligands for the TIE2 receptor. Uniquely, ANGPT2 possesses an agonistic role in lymphatic endothelium, but acts as a competitive antagonist in blood …Author: Tomokazu Souma, Benjamin R. Thomson, Stefan Heinen, Isabel Anna Carota, Shinji Yamaguchi, Tuncer Ona...

[Full text] Silica nanoparticles induce oxidative stress ...

    https://www.dovepress.com/silica-nanoparticles-induce-oxidative-stress-inflammation-and-endothel-peer-reviewed-fulltext-article-IJN
    Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling Caixia Guo,1,2 Yinye Xia,1,2 Piye Niu,1,2 Lizhen Jiang,1,2 Junchao Duan,1,2 Yang Yu,1,2 Xianqing Zhou,1,2 Yanbo Li,1,2 Zhiwei Sun1,2 1School of Public Health, 2Beijing Key Laboratory of Environmental Toxicology, Capital ...

Volume9,Issue1 - IJPCR

    https://ijpcr.com/volume9issue1/
    The encouragement in development of novel drug delivery system is apart from therapeutic efficacy is its cause. Redesigning the unit and means is a difficult task and profitable task so a controlled released drug delivery system, a novel drug delivery system evolves which facilitates the release of drug at predetermined rate.

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