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https://www.researchgate.net/publication/8053272_Drug_delivery_and_in_vitro_models_of_the_blood-brain_barrier
Drug delivery and in vitro models of the blood–brain barrier Article · Literature Review (PDF Available) in Current opinion in drug discovery & development 8(1):89-99 · February 2005 with 941 ...
https://www.ncbi.nlm.nih.gov/pubmed/26869407
Stroke and Drug Delivery--In Vitro Models of the Ischemic Blood-Brain Barrier. Tornabene E(1), Brodin B(2). Author information: (1)Section of Pharmaceutical Design and Drug Delivery, Department of Pharmacy, Faculty of Health and Medical Sciences, University of …Author: Erica Tornabene, Birger Brodin
https://www.ncbi.nlm.nih.gov/pubmed/15679176
Drug delivery and in vitro models of the blood-brain barrier. Cucullo L(1), Aumayr B, Rapp E, Janigro D. Author information: (1)Division of Cerebrovascular Research, Cleveland Clinic Foundation NB-20, Cleveland, OH 44195, USA.Author: Cucullo L, Aumayr B, Rapp E, Janigro D
https://www.sciencedirect.com/science/article/abs/pii/S0022354915001975
In vitro models of the blood-brain barrier are useful tools to investigate the effects of induced ischemia under controlled conditions. In the present mini review, we aim to give a brief overview of the in vitro models of ischemia. Special focus is given to the expression of uptake and efflux transport pathways in the ischemic and postischemic ...Author: Erica Tornabene, Birger Brodin
https://www.sciencedirect.com/science/article/pii/S0022354915001975
Stroke and Drug Delivery—In Vitro Models of the Ischemic Blood-Brain ... M. Niwa, M.A. DeliPatented in vitro blood-brain barrier models in CNS drug discovery. Recent Pat CNS Drug Discov, 6 (2) (2011), pp. 107-118. Google Scholar. 15. I. Wilhelm, I.A. KrizbaiIn vitro models of the blood-brain barrier for the study of drug delivery to the ...Author: Erica Tornabene, Birger Brodin
https://pubs.acs.org/doi/10.1021/mp500046f
Mar 18, 2014 · The most important obstacle to the drug delivery into the brain is the presence of the blood–brain barrier, which limits the traffic of substances between the blood and the nervous tissue. Therefore, adequate in vitro models need to be developed in order to characterize the penetration properties of drug candidates into the central nervous system.Author: Imola Mária Wilhelm, István Adorján Krizbai
https://pubs.acs.org/doi/abs/10.1021/mp500046f?src=recsys
Mar 18, 2014 · The most important obstacle to the drug delivery into the brain is the presence of the blood–brain barrier, which limits the traffic of substances between the blood and the nervous tissue. Therefore, adequate in vitro models need to be developed in order to characterize the penetration properties of drug candidates into the central nervous system. This review article summarizes the …Author: Imola Mária Wilhelm, István Adorján Krizbai
https://www.researchgate.net/publication/51139588_Patented_In_Vitro_Blood-Brain_Barrier_Models_in_CNS_Drug_Discovery
Background: Brain endothelial cell-based in vitro models are among the most versatile tools in blood-brain barrier research for testing drug penetration to the central nervous system.
https://www.dovepress.com/in-vitro-blood-brain-barrier-models-for-drug-screening-and-permeation--peer-reviewed-fulltext-article-DDDT
Vastag M, Keseru GM. Current in vitro and in silico models of blood-brain barrier penetration: a practical view. Curr Opin Drug Discov Devel. 2009;12(1):115–124. 63. Abbott NJ. Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models.Author: Sounak Bagchi, Tanya Chhibber, Behnaz Lahooti, Angela Verma, Vivek Borse, Rahul Dev Jayant
https://www.nature.com/articles/nrd2368
Aug 01, 2007 · Fenart, L. et al. Inhibition of P-glycoprotein: rapid assessment of its implication in blood–brain barrier integrity and drug transport to the brain by an in vitro model of the blood–brain ...Author: Romeo Cecchelli, Vincent Berezowski, Stefan Lundquist, Maxime Culot, Mila Renftel, Marie-Pierre Deho...
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