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https://www.sciencedirect.com/science/article/pii/S0169409X11002900
5.2. Transport system-mediated drug delivery across the blood–brain barrier. The combination of endogenous transport systems present in the BBB and macromolecular conjugates or surface enhanced nano-particulate delivery systems such as liposomes, nanoparticles and supermolecular complexes has been utilised to access the brain.Author: Yan Chen, Lihong Liu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388327/
The presence of the blood-brain barrier (BBB) is a significant impediment to the delivery of therapeutic agents to the brain for treatment of brain diseases. Focused ultrasound (FUS) has been developed as a non-invasive method for transiently increasing the permeability of the BBB to promote drug delivery to targeted regions of the brain.Author: Alison Burgess, Kullervo H. Hynynen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493051/
Du J, Lu WL, Ying X, Liu Y, Du P, Tian W, et al. Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumor-bearing animals. Mol Pharm. 2009; 6:905–917.Author: Tej D. Azad, James Pan, Ian D. Connolly, Austin Remington, Christy M. Wilson, Gerald A. Grant
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1567-2018&volume=1&issue=4&spage=361
A brief review of the nature of the blood-brain barrier and its transport mechanisms is provided. Strategies to target and improve transport across the blood-brain barrier include the prodrug-lipidisation approach, sequential metabolism chemical delivery systems, drug-vectors, liposomes and nanoparticles.
https://link.springer.com/article/10.1007%2Fs40263-016-0405-9
Jan 18, 2017 · Crossing the Blood–Brain Barrier: Recent Advances in Drug Delivery to the Brain ... Chen Y, Liu L. Modern methods for delivery of drugs across the blood–brain barrier. ... al. PLGA nanoparticles prepared by nano-emulsion templating using low-energy methods as efficient nanocarriers for drug delivery across the blood–brain barrier. J ...Author: Mayur M. Patel, Bhoomika M. Patel
https://www.researchgate.net/publication/236636032_Drug_Delivery_across_the_Blood-Brain_Barrier
Drug Delivery across the Blood-Brain Barrier Article in Molecular Pharmaceutics 10(5):1471-2 · May 2013 with 111 Reads How we measure 'reads'
https://www.sciencedaily.com/releases/2019/12/191212104052.htm
Dec 12, 2019 · A potent drug for glioblastoma can't be used in patients. It can't reach its target because it's blocked by the blood-brain barrier, and the conventional formulation for this drug is toxic to the ...
https://www.sciencedirect.com/science/article/pii/S0028390816303616
Efficient transcytosis across the blood-brain-barrier (BBB) is an important strategy for accessing drug targets within the central nervous system (CNS). Despite extensive research the number of studies reporting successful delivery of macromolecules or macromolecular complexes to …Author: Imre Mäger, Imre Mäger, Axel H. Meyer, Jinghuan Li, Martin Lenter, Tobias Hildebrandt, German Leparc...
https://www.slideshare.net/AmanKumarNaik/drug-delivery-across-bbb
May 06, 2016 · Drug delivery across BBB 1. 11/2015 :: National Institute of Science Education and Research :: Aman Kumar Naik Integrated M.Sc. Drug Delivery across the Blood–Brain Barrier(BBB) 2. onal adhesion molecule-1, occludin, and claudins) with cy- mic accessory proteins (zonula occludens-1 and -2, cingulin, and 7H6).
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