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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004426/
Introduction. The ARVO 2012 Summer Eye Research Conference (SERC 2012) on “Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside” was held June 15 and 16, 2012, at the University of Colorado Anschutz Medical Campus in Aurora, Colorado.Author: Cheryl L. Rowe-Rendleman, Shelley A. Durazo, Uday B. Kompella, Kay D. Rittenhouse, Adriana Di Polo, ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926814/
Conjunctival pathway, on the other hand, involves drug permeability across conjunctiva followed by entry into the sclera, choroid, retinal pigment epithelium, and retina. Drug delivery to the back of the eye from an eye drop primarily occurs via the conjunctival pathway.Author: Uday B. Kompella, Aniruddha C. Amrite, Rashmi Pacha Ravi, Shelley A. Durazo
https://www.academia.edu/28006987/Drug_and_Gene_Delivery_to_the_Back_of_the_Eye_From_Bench_to_Bedside
Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside
https://medicalxpress.com/news/2019-10-advance-drug-eluting-contact-lenses-delivery.html
Oct 02, 2019 · Drug-eluting contact lenses, which gradually release drugs into the eye, offer a promising alternative to daily eye drops, which can be unpleasant and hard for patients to properly administer. In ...
https://www.gene.com/stories/drug-delivery
Jan 13, 2020 · Traditionally, drug delivery has focused on improving the performance of existing medicines, perhaps to extend their efficacy or reduce side effects. Even though these improvements have been very successful, delivery has often been more of an afterthought in the development process.
The latest release of DrugBank (version 5.1.5, released 2020-01-03) contains 13,546 drug entries including 2,630 approved small molecule drugs, 1,372 approved biologics (proteins, peptides, vaccines, and allergenics), 131 nutraceuticals and over 6,361 experimental (discovery-phase) drugs.
https://www.liebertpub.com/doi/10.1089/jop.2012.0128
The best known systems for drug delivery to the posterior eye are intravitreal implants; in fact, some of them are being clinically used. However, their long-term accumulation might impact the patient's vision. On the contrary, colloidal drug delivery systems (microparticles, liposomes, or nanoparticles) can be easily administered in a liquid form.Author: Ana del Pozo-Rodríguez, Diego Delgado, Alicia R. Gascón, Maria Ángeles Solinís
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Ocular Drug Delivery AswAni Dutt VADlApuDi, Kishore CholKAr, supriyA reDDy DAsAri, AnD Ashim K. mitrA CHAPTER OBJECTIVES Upon completing this chapter, the reader should be able to Describe the anatomy and physiology of the eye. Understand the importance of various routes of drug administration to the eye. Describe various barriers to ocular drug delivery and constraints with
https://www.sciencedirect.com/science/article/abs/pii/S0753332218306863
The protective mechanism turns into hurdles when it comes to drug delivery especially in case of posterior segment of eye. Most common and preferable routes for ocular drug delivery are topical and systemic routes owing to their compliance and non-invasive nature, however they turned inefficient in delivering drugs to posterior segment.Author: Kritika Nayak, Manju Misra
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