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https://www.nature.com/articles/nbt.4071
Nanoscale robots have potential as intelligent drug delivery systems that respond to molecular triggers. Using DNA origami we constructed an autonomous DNA robot programmed to transport payloads and present them specifically in tumors.Author: Suping Li, Qiao Jiang, Shaoli Liu, Yinlong Zhang, Yanhua Tian, Yanhua Tian, Chen Song, Jing Wang, Yi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821297/
Feb 25, 2016 · One of the most promising assembly techniques in nano-technology is “scaffolded DNA origami” to design and construct a nano-scale drug delivery system. Because of the global health problems of tuberculosis, the development of potent new anti-tuberculosis drug delivery system without cross-resistance with known anti-mycobacterial agents is urgently needed.Author: Reza Ranjbar, Mohammad Sadegh Hafezi-Moghadam
https://techcrunch.com/2018/02/12/new-dna-nanorobots-successfully-targeted-and-killed-off-cancerous-tumors/
Feb 12, 2018 · DNA nanorobots are a somewhat new concept for drug delivery. They work by getting programmed DNA to fold into itself like origami and then deploying it like a tiny machine, ready for action.
https://bsclarified.wordpress.com/2012/03/21/dna-nanorobot-the-next-generation-of-targeted-drug-delivery-systems/
Mar 21, 2012 · Targeted Drug Delivery System These DNA robots with aptamer locks can make a great targeted drug delivery system (DDS), allowing drugs to be delivered only where it is needed and more importantly reduce side effects. The use of targeted DDS can improve medical treatments for patients, such as the case of cancer and chemotherapy.
https://pubs.acs.org/doi/abs/10.1021/acs.chemrev.7b00663
Over the past decade, we have seen rapid advances in applying nanotechnology in biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging field, DNA nanotechnology offers simple yet powerful design techniques for self-assembly of nanostructures with unique advantages and high potential in enhancing drug targeting and reducing drug toxicity.Author: Qinqin Hu, Hua Li, Lihua Wang, Lihua Wang, Hongzhou Gu, Chunhai Fan, Chunhai Fan
https://www.ncbi.nlm.nih.gov/pubmed/29431737
Nanoscale robots have potential as intelligent drug delivery systems that respond to molecular triggers. Using DNA origami we constructed an autonomous DNA robot programmed to transport payloads and present them specifically in tumors. Our nanorobot is functionalized on the outside with a DNA aptamer that binds nucleolin, a protein specifically ...Author: Suping Li, Qiao Jiang, Shaoli Liu, Yinlong Zhang, Yanhua Tian, Yanhua Tian, Chen Song, Jing Wang, Yi...
https://www.sciencedirect.com/science/article/pii/S0167779915001614
The successful delivery of DNA-based structures into cells opens new avenues for tackling diverse medical tasks. Jiang et al. and Zhang et al. managed to deliver doxorubicin – an anticancer drug and a DNA intercalator – into cells in vivo using rod-like DNA origamis or DNA …Author: Veikko Linko, Ari Ora, Mauri A. Kostiainen
https://newatlas.com/nanobots-blood-drug-delivery/38064/
Nanorobots wade through blood to deliver drugs. Nanorobots hold great potential in the field of medicine. This is largely due to the possibility of highly-targeted delivery of medical payloads, an outcome that could lessen side effects and negate the need for invasive procedures.
https://www.researchgate.net/publication/311941829_Nanorobotics_in_Drug_Delivery_Systems_for_Treatment_of_Cancer_A_Review
applied in Drug Delivery Systems. Some research uses proteins, to feed nanomotors that can move large objects, DNA hybridization, antibody protein also is used in the construction of nanorobots.
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