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https://www.sciencedaily.com/releases/2020/03/200309152051.htm
Mar 09, 2020 · Protecting DNA origami for anti-cancer drug delivery Date: March 9, 2020 Source: DOE/Brookhaven National Laboratory Summary: Scientists coated octahedral-shaped DNA origami with peptoids that help ...
https://pubs.acs.org/doi/abs/10.1021/nn502058j
The delivery of the known anticancer drug doxorubicin into tumors by self-assembled DNA origami nanostructures was performed, and this approach showed prominent therapeutic efficacy in vivo. The DNA origami carriers were prepared through the self-assembly of M13mp18 phage DNA and hun...Author: Qian Zhang, Qiao Jiang, Na Li, Luru Dai, Qing Liu, Linlin Song, Jinye Wang, Yaqian Li, Jie Tian, Bao...
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201804785
In particular, DNA‐origami nanostructures feature rationally designed geometries and precise spatial addressability, as well as marked biocompatibility, thus providing a promising candidate for drug delivery. Here, the recent successful efforts to employ self‐assembled DNA‐origami nanostructures as drug‐delivery vehicles are summarized.Author: Qiao Jiang, Shaoli Liu, Shaoli Liu, Jianbing Liu, Zhen‐Gang Wang, Baoquan Ding, Baoquan Ding, Baoqua...
https://phys.org/news/2020-03-dna-origami-anti-cancer-drug-delivery.html
Mar 09, 2020 · Protecting DNA origami for anti-cancer drug delivery. by Brookhaven National Laboratory (Top left) Structure of the octahedral-shaped DNA origami imaged with …
https://www.eurekalert.org/pub_releases/2020-03/dnl-pdo030420.php
Protecting DNA origami for anti-cancer drug delivery Scientists designed a tunable peptide-like molecular coating that enables 3D DNA nanostructures to maintain their structural integrity and ...
https://onlinelibrary.wiley.com/doi/abs/10.1002/asia.201900574
DNA nanotechnology has been employed in the construction of self‐assembled nano‐biomaterials with uniform size and shape for various biological applications, such as bioimaging, diagnosis, or therapeutics. Herein, recent successful efforts to utilize multifunctional DNA origami nanoplatforms as drug‐delivery vehicles are reviewed.Author: Xuehe Lu, Xuehe Lu, Jianbing Liu, Xiaohui Wu, Xiaohui Wu, Baoquan Ding, Baoquan Ding, Baoquan Ding
https://www.idtdna.com/pages/education/decoded/article/practical-applications-of-dna-origami
DNA origami combines a long (~8000 nt) single strand of DNA (a scaffold) with hundreds of short oligos to form a specific conformation. The resulting DNA structures can be used in applications ranging from nanorobots to controlled drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821297/
Feb 25, 2016 · Introduction. With all of the developments on infectious diseases, tuberculosis (TB) remains a cause of death among people. One of the most promising assembly techniques in nano-technology is “scaffolded DNA origami” to design and construct a nano-scale drug delivery system.Author: Reza Ranjbar, Mohammad Sadegh Hafezi-Moghadam
https://www.bnl.gov/newsroom/news.php?a=117042
Mar 09, 2020 · Protecting DNA Origami for Anti-Cancer Drug Delivery Scientists designed a tunable peptide-like molecular coating that enables 3-D DNA nanostructures to maintain their structural integrity and functionality in different physiological environments relevant to drug delivery …
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