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https://www.sciencedirect.com/science/article/pii/S0142961217307755
A similar type of nanoparticles for drug delivery was introduced by our group where the inorganic material is replaced by a soft matter core consisting of hydrophobic polymer units that are covalently attached to oligonucleotides to form DNA block copolymers .Author: Jan Willem de Vries, Sven Schnichels, José Hurst, Lisa Strudel, Agnieszka Gruszka, Minseok Kwak, Min...
https://www.machinedesign.com/materials/article/21837237/dna-barcoded-nanoparticles-identify-drugdelivery-candidates
Oct 12, 2018 · “DNA Barcoded” Nanoparticles Identify Drug-Delivery Candidates A new screening process developed at the Georgia Institute of technology …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997790/
Jan 28, 2020 · DNA nanocentipede was firstly introduced by Li et al. as a powerful delivery platform to deal with the challenges of targeted drug delivery (Li et al., 2017). The structure was similar to centipede and consist of “trunk” and “legs”, as shown in Figure 10A.Author: Qingjia Chi, Zichang Yang, Kang Xu, Chunli Wang, Huaping Liang
https://pubs.rsc.org/en/content/articlelanding/2019/sc/c9sc02640a#!
New gold and lipoic based nanocarriers for the delivery of platinum(II) and platinum(IV) drugs are developed, which allow enhanced loading of the drug on the surface of the nanocarriers and release in a pH-dependent fashion, with superior release at lower pHs which are associated with many tumours.The conjugate nanoparticles and their conjugates enter cells rapidly (within 3 hours).
https://www.ncbi.nlm.nih.gov/pubmed/29465222
May 22, 2019 · Potent anticancer drug molecules, including Doxorubicin and CpG oligonucleotides, have been successfully loaded on DNA nanostructures to increase their cell uptake efficiency. These advances have implicated the bright future of DNA nanotechnology-enabled nanomedicine.Author: Qinqin Hu, Hua Li, Lihua Wang, Lihua Wang, Hongzhou Gu, Chunhai Fan, Chunhai Fan
https://www.pnas.org/content/113/48/13600
Nov 29, 2016 · DNA-mediated nanoparticle assembly is an emerging concept to design drug delivery vehicles that can modify their structure or function in response to the in vivo environment. However, better understanding of their interactions with different tissues and …Author: Kyryl Zagorovsky, Leo Y. T. Chou, Warren C. W. Chan
https://pubs.acs.org/doi/10.1021/acs.chemrev.7b00663
Over the past decade, we have seen rapid advances in applying nanotechnology in biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging field, DNA nanotechnology offers simple yet powerful design techniques for self-assembly of nanostructures with unique advantages and high potential in enhancing drug targeting and reducing drug toxicity.Author: Qinqin Hu, Hua Li, Lihua Wang, Lihua Wang, Hongzhou Gu, Chunhai Fan, Chunhai Fan
https://pubs.acs.org/doi/abs/10.1021/acsnano.7b08620
These dimers can sense two mRNA targets and simultaneously or independently deliver one or two DNA-intercalating anticancer drugs (doxorubicin and mitoxantrone) in live cells.Author: Maria Eleni Kyriazi, Davide Giust, Afaf H. El-Sagheer, Afaf H. El-Sagheer, Peter M. Lackie, Otto L. ...
https://www.researchgate.net/publication/261118354_DNA-Conjugated_Gold_Nanoparticles_for_Ultrasound_Targeted_Drug_Delivery
A novel platform based on gold nanoparticles (Au NPs) coupled with double-stranded DNA sequences and aptamers (referred to as ds(sgc8c)-Au NPs) was developed for ultrasoundcontrolled targeted drug delivery. The sgc8c aptamers with high affinity to CCRF-CEM (T-cell leukemia)...
https://www.sciencedirect.com/science/article/pii/B9780128136898000021
Nanoparticle drug delivery systems (NPDDS) achieve superior entry for the particles inside the body, as their size permits conveyance by means of intravenous infusion or different courses. Another important use of the NPDDS is in the production of the antibodies based specific proteins against the …Author: Deepti Sharma, Navneet Sharma, Mallika Pathak, Paban K. Agrawala, Mitra Basu, Himanshu Ojha
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