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https://www.mdpi.com/1420-3049/10/1/34
Nucleic acid delivery has many applications in basic science, biotechnology, agriculture, and medicine. One of the main applications is DNA or RNA delivery for gene therapy purposes. Gene therapy, an approach for treatment or prevention of diseases associated with defective gene expression, involves the insertion of a therapeutic gene into cells, followed by expression and production of the ...Author: H. Eliyahu, Y. Barenholz, A. J. Domb
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147627/
Jan 31, 2005 · Nucleic acid delivery has many applications in basic science, biotechnology, agriculture, and medicine. One of the main applications is DNA or RNA delivery for gene therapy purposes. Gene therapy, an approach for treatment or prevention of diseases associated ...Author: H. Eliyahu, Y. Barenholz, A. J. Domb
https://www.ncbi.nlm.nih.gov/pubmed/18007276
Jan 31, 2005 · Polymers for DNA delivery. Eliyahu H(1), Barenholz Y, Domb AJ. Author information: (1)Department of Medicinal Chemistry and Natural Products, School of Pharmacy, Jerusalem, Israel. Nucleic acid delivery has many applications in basic science, biotechnology, agriculture, and medicine.Author: H. Eliyahu, Y. Barenholz, A. J. Domb
https://www.researchgate.net/publication/5840328_Polymers_for_DNA_delivery
Nucleic acid delivery has many applications in basic science, biotechnology, agriculture, and medicine. One of the main applications is DNA or RNA delivery for gene therapy purposes.
https://www.sciencedirect.com/science/article/pii/S0168365907006220
Besides, the capability to release the DNA upon degradation of the carrier has been shown in several studies, allowing controlled intracellular delivery of the DNA. PEI-based polymers with degradable or reducible linkers are very promising, because polyplexes based on these polymers show up to 20 times higher transfection activity than pEI ...Author: Jordy Luten, Cornelus F. van Nostrum, Stefaan C. De Smedt, Wim E. Hennink
https://www.sciencedirect.com/science/article/pii/S0168365999000759
Copolymers of 2-(dimethylamino)ethyl methacrylate (DMAEMA) and N-isopropylacryl amide (NIPAAm) of various monomer ratios and molecular weights were evaluated as carrier systems for DNA delivery.All copolymers, even with a low DMAEMA content of 15 mol%, were able to bind to DNA at 25°C.Author: W.L.J Hinrichs, N.M.E Schuurmans-Nieuwenbroek, P van de Wetering, W.E Hennink
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