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https://www.ncbi.nlm.nih.gov/pubmed/9822868
Diblock copolymer nanoparticles for drug delivery. Kwon GS(1). Author information: (1)School of Pharmacy, University of Wisconsin at Madison 53706-1508, USA. Diblock copolymers can form nanoparticles, that is, micelles and nanospheres, that are being …Author: Glen S. Kwon
https://conservancy.umn.edu/handle/11299/169926
Drug delivery system, as one of the chemotherapeutic treatments has received enorrmous attention from researchers. This thesis is to develop amphiphilic diblock copolymer protected nanoparticles loaded with anti-cancer drug, with small size and high drug loading, …Author: Jing Han
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000205/
Nov 26, 2010 · Due to their small particle size and large and modifiable surface, nanoparticles have unique advantages compared with other drug carriers. As a research focus in recent years, polyethylene glycol–polylactic acid (PEG–PLA) block copolymer ...Author: Ren Zhong Xiao, Zhao Wu Zeng, Guang Lin Zhou, Jun Jie Wang, Fan Zhu Li, An Ming Wang
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/plga-drug-delivery.html
Solubility enhancement of hydrophobic drugs via drug-loaded micelles using biodegradable PEG- polyester diblock copolymers The requirement for large quantities of saline to dissolve such materials limits their clinical use, and one solution for this problem that has recently generated interest is the formation of drug-loaded micelles.
https://pubs.acs.org/doi/abs/10.1021%2Facs.biomac.7b01279
Functional block copolymers based on poly(2-oxazoline)s are versatile building blocks for the fabrication of dual-drug delivery nanoparticles (NPs) for anticancer chemotherapy. Core–shell NPs are fabricated from diblock copolymers featuring a long and hydrophilic poly(2-methyl-2-oxazoline) (PMOXA) block coupled to a relatively short and functionalizable poly(2-methylsuccinate-2-oxazoline ...Author: Matteo Romio, Giulia Morgese, Lucca Trachsel, Samuel Babity, Cristina Paradisi, davide brambilla, Ed...
https://pubs.acs.org/doi/10.1021/ma502339s
We present a facile and versatile approach to prepare diblock copolymer based Janus nanoparticles (NPs). Diblock copolymer PS-b-P4VP can self-assemble into patchy particles with P4VP protuberances on their surface using the emulsion solvent evaporation method. After cross-linking the P4VP protuberances, Janus NPs are produced by disassembling the particles. Within the P4VP domains, …Author: Renhua Deng, Fuxin Liang, Xiaozhong Qu, Qian Wang, Jintao Zhu, Zhenzhong Yang
https://www.sciencedirect.com/science/article/pii/S0378517313005917
Synthesis and micellization of a pH-sensitive diblock copolymer for drug delivery. ... is the mass fraction of the hydrophilic block to the total polymer mass and is what dictates the structure of the nanoparticles. For diblock amphiphilic ... A. Harada, Y. NagasakiBlock copolymer micelles for drug delivery: design, characterization and ...Author: Konstantinos P. Koutroumanis, Richard G. Holdich, Stella Georgiadou
https://www.sciencedirect.com/science/article/pii/S0142961213010983
This study systematically compares the effects of amphiphilic diblock copolymer (di-BCP) on stabilizing hydrophobic drug nanoparticles formed by flash nanoprecipitation (FNP), and provides a guideline on choosing suitable di-BCPs.Author: Zhengxi Zhu
https://www.onlinelibrary.wiley.com/doi/10.1002/marc.201800917
pH‐Responsive Polymer Nanoparticles for Drug Delivery. Nayeleh Deirram. School of Chemistry, The University of Melbourne, Parkville, Victoria, 3010 Australia ... For drug delivery applications two types of polymers are commonly used, ... (2‐diethylamino)ethyl methacrylate) (PDEAEMA) (38 kDa) and a diblock copolymer poly ...Author: Nayeleh Deirram, Changhe Zhang, Sarah S. Kermaniyan, Angus P. R. Johnston, Georgina K. Such
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