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https://www.sciencedirect.com/science/article/pii/B9780128179093000054
Copolymers and block copolymers are employed widely in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo …Author: Nidhi Raval, Dnyaneshwar Kalyane, Rahul Maheshwari, Rakesh K. Tekade
https://www.ncbi.nlm.nih.gov/pubmed/9822868
Diblock copolymer nanoparticles for drug delivery. Kwon GS(1). Author information: (1)School of Pharmacy, University of Wisconsin at Madison 53706-1508, USA. Diblock copolymers can form nanoparticles, that is, micelles and nanospheres, that are being …Author: Glen S. Kwon
https://www.nature.com/articles/42218
Aug 28, 1997 · Biodegradable polymers used for drug delivery to date have mostly been in the form of injectable microspheres or implant systems, which require complicated fabrication processes using …Author: Byeongmoon Jeong, You Han Bae, Doo Sung Lee, Sung Wan Kim
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/plga-drug-delivery.html
Solubility enhancement of hydrophobic drugs via drug-loaded micelles using biodegradable PEG- polyester diblock copolymers One of the common difficulties with intravenous drug delivery is low solubility of the drug.
https://pubs.rsc.org/en/content/articlepdf/2020/sc/d0sc00569j
viscosity modi ers,8 stem cell storage media9 and drug delivery.10 The rst example of well-de ned diblock copolymers were prepared by anionic polymerization.11 This living polymeriza-tion technique allows the synthesis of copolymer chains with very narrow molecular weight distributions but …
https://conservancy.umn.edu/bitstream/handle/11299/169926/Han_umn_0130E_15487.pdf;sequence=1
Diblock Copolymer Stabilized Nanoparticles for Drug Delivery via Flash Nanoprecipitation A Dissertation SUBMITTED TO THE FACULTY OF UNIVERSITY OF MINNESOTA BY Jing Han IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY Christopher W. Macosko October 2014
https://pubs.acs.org/doi/10.1021/bm0508921
Block copolymer micelles with acid-labile ortho ester side-chains: Synthesis, characterization, and enhanced drug delivery to human glioma cells. Journal of Controlled Release 2011 , 151 (1) , 18-27.Author: Cristiano Giacomelli, Lucile Le Men, Redouane Borsali, Joséphine Lai-Kee-Him, Alain Brisson, Steven ...
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/poly-amino-acid-block-copolymers.html
When used as drug delivery vehicles, amphiphilic diblock copolymers generally self-assemble into classic spherical polymeric micelles upon exposure to a selective solvent such as water (Figure 2A). In most cases, the hydrophobic segment packs tightly to avoid contact with the water and the hydrophilic segment readily solubilizes to form a shell or corona around the hydrophobic core.
https://pubs.acs.org/doi/10.1021/la950649v
Morphology prediction of block copolymers for drug delivery by mesoscale simulations. Journal of Materials Chemistry 2010, 20 (36) , 7742. DOI: 10.1039/c0jm01301c. ... Mixed micelle systems formed from critical micelle concentration and temperature-sensitive diblock copolymers for doxorubicin delivery. Biomaterials 2009, 30 (23-24) , 3961-3970 ...Author: S. A. Hagan, A. G. A. Coombes, M. C. Garnett, S. E. Dunn, M. C. Davies, and L. Illum, S. S. Davis, S...
https://www.sciencedirect.com/science/article/pii/S0168365905004906
Beyond solubilizing hydrophobic drugs, block copolymer micelles can also target their payload to specific tissues through either passive or active means. Prolonged in vivo circulation times and adequate retention of the drug within the carrier are prerequisites to successful drug targeting.Author: Geneviève Gaucher, Marie-Hélène Dufresne, Vinayak P. Sant, Ning Kang, Dusica Maysinger, Jean-Christo...
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