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https://www.ncbi.nlm.nih.gov/pubmed/9822868
Several studies have illustrated prolonged residence times in blood for diblock copolymer nanoparticles. They have also enhanced drug effects in animals. Diblock copolymer nanoparticles are potentially useful carriers for site-specific drug delivery.Author: Glen S. Kwon
https://conservancy.umn.edu/handle/11299/169926
Cancer is one of the most challenge diseases to treat around the world. Drug delivery system, as one of the chemotherapeutic treatments has received enorrmous attention from researchers. This thesis is to develop amphiphilic diblock copolymer protected nanoparticles loaded with anti-cancer drug, with small size and high drug loading,...Author: Jing Han
https://www.onlinelibrary.wiley.com/doi/10.1002/marc.201800917
Abstract. Stimuli‐responsive nanoparticles have the potential to improve the delivery of therapeutics to a specific cell or region within the body. There are many stimuli that have shown potential for specific release of cargo, including variation of pH, redox potential, or the presence of enzymes.Author: Nayeleh Deirram, Changhe Zhang, Sarah S. Kermaniyan, Angus P. R. Johnston, Georgina K. Such
https://www.sciencedirect.com/science/article/pii/B9780081019979000151
NPs are used as vectors for the applications in drug delivery, gene delivery, or as biosensors, where a direct contact with blood occurs. For blood contact applications, biocompatibility is determined largely by specific interactions with blood and its components.Author: Rajesh K. Saini, Laxmi P. Bagri, Anil K. Bajpai, Abhilasha Mishra
https://pubs.acs.org/doi/abs/10.1021%2Facs.biomac.7b01279
Functional block copolymers based on poly(2-oxazoline)s are versatile building blocks for the fabrication of dual-drug delivery nanoparticles (NPs) for anticancer chemotherapy. Core–shell NPs are fabricated from diblock copolymers featuring a long and hydrophilic poly(2-methyl-2-oxazoline) (PMOXA) block coupled to a relatively short and functionalizable poly(2-methylsuccinate-2-oxazoline) (PMestOXA) …Author: Matteo Romio, Giulia Morgese, Lucca Trachsel, Samuel Babity, Cristina Paradisi, davide brambilla, Ed...
https://www.sciencedirect.com/science/article/pii/S0079670010000663
Block copolymers used in drug delivery with polymers other than PEG as the hydrophilic block. Though the use of PEG for drug delivery applications is common, these structures illustrate alternatives. The hydrophobic block of the final structure, PDPA, is an example of a pH-sensitive polymer.Author: Zachary L. Tyrrell, Youqing Shen, Youqing Shen, Maciej Radosz
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