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https://www.ncbi.nlm.nih.gov/pubmed/21181549
Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Wijagkanalan W(1), Kawakami S, Hashida M. Author information: (1)Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan. [email protected]: Wassana Wijagkanalan, Wassana Wijagkanalan, Shigeru Kawakami, Mitsuru Hashida
https://link.springer.com/article/10.1007/s11095-010-0339-8
Dec 23, 2010 · A better understanding of the basic aspects of dendritic systems and their pharmacokinetics will help to develop a rationale for the design of dendrimers for the controlled delivery of drugs and imaging reagents for therapeutic or diagnostic purposes.Author: Wassana Wijagkanalan, Wassana Wijagkanalan, Shigeru Kawakami, Mitsuru Hashida
https://www.researchgate.net/publication/49705440_Designing_Dendrimers_for_Drug_Delivery_and_Imaging_Pharmacokinetic_Considerations
Request PDF Designing Dendrimers for Drug Delivery and Imaging: Pharmacokinetic Considerations Dendrimers have well-organized high branches with a layered architecture providing a series of ...
https://www.researchgate.net/publication/320353147_Dendrimers_in_anticancer_drug_delivery
Designing Dendrimers for Drug Delivery and Imaging: Pharmacokinetic Considerations. ... for the design of dendrimers for the controlled delivery of drugs and imaging reagents for therapeutic or ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685189/
Jun 01, 2013 · COMPARATIVE PHARMACOKINETICS OF PAMAM-OH DENDRIMERS AND HPMA COPOLYMERS IN OVARIAN-TUMOR-BEARING MICE ... Biocompatible water-soluble polymers have been widely used as carriers for a variety of drug-delivery and in vivo imaging applications ... Hashida M. Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Pharm ...Author: S. Sadekar, O. Linares, G. J. Noh, D. Hubbard, A. Ray, M. Janát-Amsbury, C. M. Peterson, J. Facelli,...
https://pubs.acs.org/doi/10.1021/mp050023q
Jun 22, 2005 · Starpharma focuses on the use of dendrimers as drugs in their own right, in contrast to dendrimers as drug delivery vehicles or diagnostics. This contextual review describes how dendrimers offer a unique platform for exploring chemical diversity on the nanoscale and how the production of dendrimer libraries covering a diverse array of macromolecular structures can be used in drug …Author: Tom D. McCarthy, Peter Karellas, Scott A. Henderson, Michael Giannis, David F. O'Keefe, Graham Heery...
https://pubs.acs.org/doi/10.1021/mp060032e
Cationic poly-l-lysine 3H-dendrimers with either 16 or 32 surface amine groups (BHALys [Lys]4 [3H-Lys]8 [NH2]16 and BHALys [Lys]8 [3H-Lys]16 [NH2]32, generation 3 and 4, respectively) have been synthesized and their pharmacokinetics and biodistribution investigated after intravenous administration to rats. The species in plasma with which radiolabel was associated was also investigated by size ...Author: Benjamin James Boyd, Lisa Michelle Kaminskas, Peter Karellas, Guy Yeoman Krippner, Romina Lessene, C...
https://www.sciencedirect.com/science/article/pii/S1359644610000334
Potential applications of dendrimers. (a) Dendrimer drug conjugates, dendrimers linked to targeting moieties and imaging agents. (b) Encapsulation of the drugs in the dendritic interiors. (c) Dendrimers incorporated into various delivery systems for enhancing permeation, solubility and so on. (d) Dendrimers as complexing agents.Author: Anupa R. Menjoge, Anupa R. Menjoge, Rangaramanujam M. Kannan, Rangaramanujam M. Kannan, Donald A. To...
https://link.springer.com/journal/11095/28/7
Jul 07, 2011 · Designing Dendrimers for Drug Delivery and Imaging: Pharmacokinetic Considerations. Wassana Wijagkanalan, Shigeru Kawakami, Mitsuru Hashida Pages 1500-1519. Research Paper. Agarose Surface Coating Influences Intracellular Accumulation and Enhances Payload Stability of a Nano-delivery System.
https://www.sciencedirect.com/science/article/pii/B9780128145272000044
For the development of the delivery system, pharmacokinetic profiling is very much required as it indicates the fate of the delivery system in the body and displays about the potential toxic or beneficial events . 2. Effect of size, molecular weight, hydrophobicity and charge on pharmacokinetic profile of …Author: Lakshmi Tunki, Hitesh Kulhari, Suresh K. Bhargava, Deep Pooja
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