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https://www.sciencedirect.com/science/article/pii/S1461534799002035
This makes it possible to selectively conjugate several different moieties, such as drug molecules, solubilizing groups and targeting groups, on the same dendritic macromolecule. In a preliminary experiment with a simplified design, we examined the conjugation of folic acid and methotrexate (MTX) to dendrimers [K.Author: Mingjun Liu, Jean M.J. Fréchet
https://www.sciencedirect.com/science/article/abs/pii/S1461534799002035
Triazine dendrimers as drug delivery systems: From synthesis to therapy Advanced Drug Delivery Reviews, Volume 64, Issue 9, 2012, pp. 826-835 Download PDF View detailsAuthor: Mingjun Liu, Jean M.J. Fréchet
https://www.ncbi.nlm.nih.gov/pubmed/21181549
Designing dendrimers for drug delivery and imaging: pharmacokinetic considerations. Wijagkanalan W(1), Kawakami S, Hashida M. Author information: (1)Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan. [email protected]: Wassana Wijagkanalan, Wassana Wijagkanalan, Shigeru Kawakami, Mitsuru Hashida
https://www.sciencedirect.com/science/article/abs/pii/S0223523409005194
The solubility in water of these charged dendrimers depends on the generation considered: generation 0 (3 carteolol) is well soluble, whereas generation 1 (6 carteolol) and generation 2 (12 carteolol) are poorly soluble. These dendrimers have been tested in vivo, as vehicle for …
https://kundoc.com/pdf-designing-dendrimers-for-ocular-drug-delivery-.html
Methods for drug delivery experiments Carteolol or dendrimers 13-Gn (n ¼ 0, 1, 2) were dissolved in milliQ water 1 min before instillation, and one drop (50 mL) of the carteolol/dendrimer solution was administered in each eye.
https://www.sciencedirect.com/science/article/pii/S0223523409005194
Original article Designing dendrimers for ocular drug delivery 1. Introduction. Dendrimers constitute nowadays a ubiquitous type of precisely defined polymers [1],... 2. Results and discussion. As indicated in the introduction, the interaction between a dendrimer... 3. Conclusions. We have ...Author: Grégory Spataro, Grégory Spataro, François Malecaze, Cédric-Olivier Turrin, Cédric-Olivier Turrin, V...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · PAMAM dendrimers are one of the most used dendrimers for drug delivery systems [5,6,7]. The dendrimer architecture has three main sites for drug entrapment by using various mechanisms: (i) void spaces (by molecular entrapment); (ii) branching points (by hydrogen bonding); and (iii) outside surface groups by (charge–charge interactions) ( Figure 1 ).Author: Abhay Singh Chauhan
https://www.researchgate.net/publication/49705440_Designing_Dendrimers_for_Drug_Delivery_and_Imaging_Pharmacokinetic_Considerations
With a focus on dendrimers, these CNDP-directed nano-periodic patterns are used as a strategy for designing and optimizing nanoparticles for a variety of drug delivery and imaging applications,...
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