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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692493/
Jun 01, 2009 · Non-viral Methods for siRNA Delivery. Kun Gao 1 and Leaf Huang ... Non-viral vectors for siRNA delivery. Of primary consideration in deciding on a drug delivery system for siRNA is whether the intended disease target lends itself to systemic or local administration. In the case of delivery of DNA encoding for the short hairpin RNA (shRNA) by ...Author: Kun Gao, Leaf Huang
https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
The main limitation of non-viral systems is their low transfection efficiency, although it has been improved by different strategies and the efforts are still ongoing ; actually, advances of non-viral delivery have lead to an increased number of products entering into clinical trials. However, viral vector has dominated the clinical trials in ...Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís
https://www.europepmc.org/articles/PMC2692493/
May 01, 2009 · Europe PMC is an archive of life sciences journal literature. Non-viral vectors for siRNA delivery. Of primary consideration in deciding on a drug delivery system for siRNA is whether the intended disease target lends itself to systemic or local administration.Author: Kun Gao, Leaf Huang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · Physical methods of nonviral gene delivery. Physical methods applied for in vitro and in vivo gene delivery are based on making transient penetration in cell membrane by mechanical, electrical, ultrasonic, hydrodynamic, or laser-based energy so …
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