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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Considering this, the present review has focused on the different strategies of their synthesis, drug delivery and targeting, gene delivery and other biomedical applications, interactions involved in formation of drug-dendrimer complex along with characterization techniques employed for their evaluation, toxicity problems and associated ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
Apr 18, 2018 · Multiple drug delivery systems: PAMAM dendrimers were evaluated to explore the potential of PAMAM dendrimers for multiple drug delivery. We have entrapped two anti-hypertensive drugs Ramipril (RAPL) and hydrochlorothiazide (HCTZ ). The results showed that the solubility of RAPL and HCTZ was dependent on dendrimer concentrations and pH of ...Author: Abhay Singh Chauhan
https://www.starpharma.com/drug_delivery
Dendrimer Drug Delivery (DEP®) Starpharma’s dendrimers can be used to enhance the properties of other drugs. The approach is known as “drug delivery” because it is about working to ensure that the drug is delivered to the right part of the body at the right time.
https://www.sciencedirect.com/science/article/pii/S0079670013000853
The expression dendrimer is derived from a Greek term dendron that means “tree”, which is logical in view of their typical structure with a number of branching units. Dendrimers are defined as synthetic macromolecules characterized by high branching points, three dimensional globular shape, monodispersity and nanometric size range.Author: Prashant Kesharwani, Keerti Jain, Narendra Kumar Jain
https://www.sciencedirect.com/science/article/pii/S2352940718301641
Targeted PAMAM dendrimer for co-delivery of a drug and siRNA. (a) Doxorubicin and siRNA against major vault protein (MVP), plus hyaluronic acid (as a targeting agent) were conjugated to PAMAM dendrimer. (b) Hyaluronic acid interacted with its receptor CD44. (c) Complex was taken up by receptor-mediated endcytosis.Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://www.hindawi.com/journals/jnm/2014/507273/
In recent years, the application of dendrimers in biomedicine attracted much attention from scientists. Dendrimers are interesting for biomedical applications because of their characteristics, including: a hyperbranching, well-defined globular structures, excellent structural uniformity, multivalency, variable chemical composition, and high biological compatibility. In particular, the three ...Author: B. Noriega-Luna, Luis A. Godínez, Francisco J. Rodríguez, A. Rodríguez, G. Zaldívar-Lelo de Larrea, ...
http://www.pharmtech.com/role-dendrimers-topical-drug-delivery
Nov 02, 2008 · This review provides an update of how dendrimer technology is being applied to the development of novel systems for various topical delivery applications. ... The Role of Dendrimers in Topical Drug Delivery.
https://www.slideshare.net/AnilPethe/dendrimers-in-drug-delivery-107157133
Jul 23, 2018 · Dendrimer–Drug Conjugates In dendrimer–drug conjugates, the drug is attached through a covalent bond either directly or via a linker/spacer to the surface groups of a dendrimer. Dendrimers have been conjugated to various biologically active molecules such as drugs, antibodies, sugar moieties and lipids Mechanism of drug delivery: Dendrimer
https://www.pharmatutor.org/articles/dendrimers-novel-drug-delivery-overview
Dendrimer as a drug delivery agent is a promising, safe and selective drug delivery option. It’s highly selective nature for targeting the desired tissue is the most essential property and holds a promising future for the treatment of several disorders.
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