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https://www.sciencedirect.com/science/article/pii/B978008100736500017X
Peptide-based systems as delivery vectors of drugs for neurodegenerative diseases Neurodegenerative diseases are considered to be caused by mitochondrial dysfunctions with subsequent oxidative stress accumulation.Author: Dana M. Copolovici, Andreea I. Lupitu
https://www.mdpi.com/journal/pharmaceutics/special_issues/peptide_DDS
Peptides are found as an alternative candidate compared to other drug delivery systems due to their safety, easy functionalization with various pharmaceutical candidates, robustness of synthetic methodology, availability to use natural or unnatural amino acids, targeting with biomarker ligands, and use of peptidomimetics to improve pharmacokinetics property.
https://www.mdpi.com/1420-3049/22/12/2185/pdf
Peptide-Based Drugs and Drug Delivery Systems Stefania Galdiero 1,2, * ID and Paula A. C. Gomes 3, * ID 1 Department of Pharmacy, School of Medicine, University of …Author: Stefania Galdiero, Paula A. C. Gomes
https://www.genengnews.com/magazine/297/optimizing-the-delivery-of-peptide-based-therapeutics/
The Medici Drug Delivery System is a matchstick-sized osmotic minipump that is placed just under the dermal layer of the skin to deliver a continuous and consistent flow of medication.
http://www.globalresearchonline.net/journalcontents/v12-1/007.pdf
DELIVERY OF PEPTIDE BASED PHARMACEUTICALS FOR SYSTEMIC MEDICATION A) PARENTERAL SYSTEMIC DELIVERY General consideration A wide variety of delivery systems exist for drug substances but currently, peptide and protein drugs are marketed almost exclusively for parenteral administration. Parenteral administration is believed to
https://www.sciencedirect.com/science/article/pii/B9780081007365000090
A smart biopolymer-based targeted delivery system is a promising strategy for delivery of various kinds of bioactive molecules including peptides. In addition, peptide biopharmaceuticals are widely investigated for targeted drug delivery as targeting agents or active ingredients of drugs.Author: Dominic Agyei, Kei-Xian Tan, Sharadwata Pan, Chibuike C. Udenigwe, Michael K. Danquah
https://www.researchgate.net/publication/319122467_An_over_view_Protein_and_peptide_based_drug_delivery
Proteins are polymers consisting of amino acids covalently linked by peptide bonds. Peptides are small proteins composed of up to a few dozen amino acids proteins are rapidly degraded by digestive enzymes. Till recently, injections (i.e. intravenous, intramuscular or subcutaneous route)...
https://www.pharmaceuticalprocessingworld.com/peptide-synthesis-in-pharmaceutical-manufacturing/
Jun 22, 2009 · Peptide-based therapies tap into the direct hard wiring of human physiology, yielding substantial and far-reaching benefits to drug treatments and therapies. Moreover, developments in peptide manufacturing and implementation have made these amino acid compounds more accessible to the market in terms of cost, flexibility, and effectiveness.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
As oral delivery improves patient compliance, there is great interest in the development of systems that allow for the oral delivery of peptide and protein therapeutics . This review will summarize the barriers to various noninvasive delivery methods with a focus on oral and transdermal delivery.Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374550/
Banga et al. was investigated and studied the hydrogel-based iontotherapeutic devices as the drug reservoir matrix for peptide-based pharmaceuticals, and the iontophoresis release and transdermal delivery of three model peptides, insulin, calcitonin, and vasopressin. The experimental results shown that permeability coefficients for these peptides across the hairless rat skin were evaluated using the hydrogel formulations prepared from polyacrylamide, p-HEMA…
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