Delivery Drug Oral Peptide Protein

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Protein and Peptide Drug Delivery: Oral Approaches

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
    Thus, we can achieve site-specific drug delivery by the use of mucoadhesive polymeric system. Mucoadhesive polymers are able to adhere to the mucin layer on the mucosal epithelium and thus results in the increase of oral drug bioavailability of protein and peptide drugs.

Nanoparticles: Oral Delivery for Protein and Peptide Drugs

    https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
    protein polypeptide drug. BARRIERS TO ORAL DELIVERY OF PROTEIN AND PEPTIDE DRUG NPS Most of the protein and peptide drugs are macromolec-ular hydrophilic, in the extreme environment of gastrointes-tinal stability, susceptible to gastric acid and pepsin degradation; at the same time, because of its hydrophilicity,Author: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun

Peptide and Protein Delivery ScienceDirect

    https://www.sciencedirect.com/book/9780123849359/peptide-and-protein-delivery
    The development of a successful oral peptide/protein delivery system has been actively investigated for the past few decades and is still a challenging area of research. Recent advances in biochemistry and biotechnology have led to the discovery and mass production of therapeutic peptides and proteins. ... Drug delivery via the paracellular ...

ORAL PEPTIDE DELIVERY: TECHNOLOGY LANDSCAPE & CURRENT ...

    https://www.ondrugdelivery.com/review-oral-peptide-delivery/
    PROTEIN ORAL DELIVERY TECHNOLOGY POD ™ POD technology developed by Oramed (Jerusalem, Israel), consists of enteric-coated capsules containing an oily suspension of the peptide drug, an enzyme inhibitor, such as soy bean trypsin inhibitor, aprotinin and an absorption enhancer such as EDTA or bile salt, in omega-3 fatty acids.

Is the oral route possible for peptide and protein drug ...

    https://www.sciencedirect.com/science/article/pii/S1359644606003084
    To develop and improve oral delivery systems with such properties, the focus should be on the development of superior materials and delivery carriers for oral bioactive macromolecular drug delivery systems. The oral route for peptide and protein drug delivery might be possible in the near future using innovative delivery systems.Author: Mariko Morishita, Nicholas A. Peppas

Basics and recent advances in peptide and protein drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
    As oral delivery improves patient compliance, there is great interest in the development of systems that allow for the oral delivery of peptide and protein therapeutics . This review will summarize the barriers to various noninvasive delivery methods with a focus on oral and transdermal delivery.Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim

Protein and peptide drug delivery: Oral approaches

    https://www.ijpsonline.com/articles/protein-and-peptide-drug-delivery-oral-approaches.html
    Nov 10, 2006 · Chemical modification and use of mucoadhesive polymeric system for site-specific drug delivery seen to be promising candidates for protein and peptide drug delivery. References . Rick S. Oral protein and peptide drug delivery. In: Binghe W, Teruna S, Richard AS, editors. Drug delivery: Principles and applications.Author: Jessy Shaji, V Patole

protein and peptide drug delivery system

    https://www.slideshare.net/BrajeshKumar67/protein-and-peptide-drug
    May 24, 2015 · protein and peptide drug delivery system 1. PROTEIN AND PEPTIDE DRUG DELIVERY SYSTEM PRESENTED BY BRAJESH KUMAR M. PHARM (1ST YEAR) PHARMACEUTICS BBAU LUCKNOW , 1 2. Contents I. Protein & Peptides II. Structure of protein III. Classification of protein IV. Drug delivery system V. Stability testing VI. Conclusion VII. References 2 3.

Nanoparticles: Oral Delivery for Protein and Peptide Drugs ...

    https://link.springer.com/article/10.1208/s12249-019-1325-z
    May 20, 2019 · METHODS TO PROMOTE THE ORAL DELIVERY OF PROTEIN AND PEPTIDE DRUG NPs. Although it has been proved that the nanoparticles can be absorbed by the GT after oral administration, low absorption is the biggest obstacle to the development of oral nanoscale drug delivery systems. With the further research of absorption mechanism, many methods to ...Author: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun

Advances in oral peptide therapeutics Nature Reviews ...

    https://www.nature.com/articles/s41573-019-0053-0
    Dec 17, 2019 · Oral delivery of peptide therapeutics could have benefits for treatment adherence, but it faces barriers related to the structural organization and physiological function of the gastrointestinal ...Author: Daniel J. Drucker

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