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http://spider.science.strath.ac.uk/sipbs/media/40/Cucurbituril_drug_delivery_review_-.pdf
The formation of drug-CB[n] host-guest complexes may provide many benefits, including: increased drug chemical and physical stability, improved drug solubility and controlled drug release. In this review paper we examine the potential use of cucurbiturils in drug delivery,
https://www.researchgate.net/publication/257816080_Cucurbiturils_in_Drug_Delivery_And_For_Biomedical_Applications
Cucurbiturils in Drug Delivery And For Biomedical Applications. ... Cucurbiturils in Drug Delivery. And For Biomedical Applications. NA’IL SALEH,* a. INDRAJIT GHOSH. b. AND. WERNER M. NAU* b. a.
https://www.frontiersin.org/articles/10.3389/fchem.2019.00619/full
Sep 13, 2019 · The supramolecular chemistry of cucurbit[n]urils (CBn) has been rapidly developing to encompass diverse medicinal applications, including drug formulation and delivery, controlled drug release, and sensing for bioanalytical purposes. This is made possible by their unique recognition properties and very low cytotoxicity. In this review, we summarize the host-guest complexation of …Author: Debapratim Das, Khaleel I. Assaf, Khaleel I. Assaf, Werner M. Nau
https://www.researchgate.net/publication/285689727_Cucurbiturils_in_Drug_Binding_and_Delivery
Here we examine the potential use of cucurbiturils in drug delivery in the context of getting a new drug into clinical trials and discuss what further research is needed in this area.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893214/
As a new cucurbituril homologue, no drug delivery studies of CB[14] have yet been undertaken . To realise the drug delivery potential of cucurbiturils they must be formulated into appropriate dosage forms for human use, but to date there has been little investigation into cucurbituril formulation.Author: Marian Seif, Michael L. Impelido, Michael G. Apps, Nial J. Wheate
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234176/
Nov 01, 2014 · The cucurbituril family of drug delivery vehicles have been examined for their tissue specific toxicity using ex vivo models. Cucurbit[6]uril (CB[6]), cucurbit[7]uril (CB[7]) and the linear cucurbituril-derivative Motor2 were examined for their neuro-, myo- and cardiotoxic activity and compared with β-cyclodextrin.Author: Rabbab Oun, Rafael S. Floriano, Lyle Isaacs, Edward G. Rowan, Nial J. Wheate
https://pubs.rsc.org/en/content/chapter/bk9781849736589-00164/978-1-84973-658-9
This chapter illustrates the potential of cucurbiturils, a synthetic class of macrocycles, as well as their derivatives and analogues for drug delivery applications, attempting a comprehensive coverage of the rapidly unfolding scholarly activity in this area up to including early 2013.Author: Na’il Saleh, Indrajit Ghosh, Werner M. Nau
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