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https://www.researchgate.net/publication/235355691_Cucurbituril_Receptors_and_Drug_Delivery
Request PDF Cucurbituril Receptors and Drug Delivery The relatively new family of molecular host–guest macrocycles known as cucurbit[n]uril is discussed in the context of a drug delivery system.
https://onlinelibrary.wiley.com/doi/abs/10.1002/9780470661345.smc056
The relatively new family of molecular host–guest macrocycles known as cucurbit[n]uril is discussed in the context of a drug delivery system.In less than a decade, cucurbit[n]uril and cucurbit[n]uril‐based supramolecular structures have emerged as promising vehicles for drug delivery.For the first time, this review brings together the results of cucurbit[n]uril‐drug studies and provides ...Author: Anthony Ivan Day, J. Grant Collins
http://spider.science.strath.ac.uk/sipbs/media/40/Cucurbituril_drug_delivery_review_-.pdf
Cucurbituril and their drug host-guest complex solubility . It was originally thought that one of the biggest hurdles to the successful use of cucurbiturils in drug delivery may have been their perceived poor aqueous solubility. Many drugs are only therapeutically active at millimolar concentrations , and in some cases those that are active at
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789246/
Efficient and site-specific delivery of therapeutic drugs is a critical challenge in clinical treatment of cancer. Nano-sized carriers such as liposomes, micelles, and polymeric nanoparticles have been investigated for improving bioavailability and pharmacokinetic properties of therapeutics via various mechanisms, for example, the enhanced permeability and retention (EPR) effect.Author: Bo Yu, Heng Chiat Tai, Weiming Xue, L. James Lee, Robert J. Lee
https://www.frontiersin.org/articles/10.3389/fchem.2019.00619/full
Sep 13, 2019 · The supramolecular chemistry of cucurbit[n]urils (CBn) has been rapidly developing to encompass diverse medicinal applications, including drug formulation and delivery, controlled drug release, and sensing for bioanalytical purposes. This is made possible by their unique recognition properties and very low cytotoxicity. In this review, we summarize the host-guest complexation of …Author: Debapratim Das, Khaleel I. Assaf, Khaleel I. Assaf, Werner M. Nau
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