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http://www.vetmed.vt.edu/clinical-trials/canine-glioma/convection-enhanced-delivery.asp
Convection Enhanced Delivery (CED) is a therapeutic strategy that was developed to facilitate targeted delivery of pharmaceuticals to the brain. The CED procedure involves a minimally invasive surgical exposure of the brain, followed by placement of small diameter catheters directly into the brain tumor. Subsequently, infusion of therapeutics into the tumor occurs over several hours to saturate the target …
https://braintumorcenter.ucsf.edu/treatment/experimental-diagnostics-therapies/convection-enhanced-delivery
To address this problem, researchers at UCSF and elsewhere have been developing a procedure called convection-enhanced delivery (CED). CED is an experimental technique for directly infusing drugs into a brain tumor. This increases drug efficacy while reducing side effects to …
https://cancerres.aacrjournals.org/content/65/15/6858
Aug 01, 2005 · Convection-enhanced drug delivery (CED) is a novel approach to directly deliver drugs into brain tissue and brain tumors. It is based on delivering a continuous infusion of drugs via intracranial catheters, enabling convective distribution of high drug concentrations over large volumes of the target tissue while avoiding systemic toxicity.Author: Yael Mardor, Ofer Rahav, Yacov Zauberman, Zvi Lidar, Aharon Ocherashvilli, Dianne Daniels, Yiftach R...
https://surgicalneurologyint.com/surgicalint-articles/convection-enhanced-drug-delivery-for-gliomas/
Interstitial drug administration via convection-enhanced delivery (CED) is an alternative that potentially overcomes systemic toxicities and CNS delivery issues by …
https://www.frontiersin.org/articles/10.3389/fonc.2019.00966/full
Convection-enhanced delivery (CED) is a technique that harnesses increased flow of fluid to increase transport of large molecules and drugs throughout a tissue. In brain cancer therapy, this technique has been implemented for decades but has not been adopted widely in the clinic.Author: Caleb A. Stine, Jennifer M. Munson
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