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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Introduction. Targeted drug delivery into the colon is highly desirable for local treatment of a variety of bowel diseases such as ulcerative colitis, Crohn’s disease, amebiosis, colonic cancer, local treatment of colonic pathologies, and systemic delivery of protein and peptide drugs.1, 2 The colon specific drug delivery system (CDDS) should be capable of protecting the drug en route to the ...Author: Anil K. Philip, Betty Philip
https://www.slideshare.net/GajananSanap/colon-targeted-drug-delivery-systems
Feb 27, 2016 · 2 In vivo methods: Animal models Rats, mice, pigs and dogs animal models were reported for colon targeted drug delivery systems. For simulating the human physiological environment of the colon, appropriate animal model selection is depends on its approach and design of system. For example, guinea pigs have glycosidase and glucuronidase ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508299/
Jun 13, 2015 · The development of colon-targeted oral drug delivery systems has gained increasing interest among formulation scientists in recent years. As discussed above, colon-specific drug delivery systems provide significant therapeutic benefits to the patients in terms of …Author: Seth Amidon, Jack E. Brown, Vivek S. Dave
https://www.researchgate.net/publication/244994822_Colon_targeted_drug_delivery_systems-A_review
Colon targeted drug delivery systems-A review Article (PDF Available) in Russian Journal of Biopharmaceuticals 3(4) · June 2011 with 10,497 Reads How we measure 'reads'
https://ijpsr.com/bft-article/colon-targeted-drug-delivery-system-a-review/?view=fulltext
b) Colon-Targeted Delivery Capsule based on pH sensitivity and Time-Release principles: The system contains an organic acid that is filled in a hard gelatin capsule as a pH-adjusting agent together with the drug substance. This capsule is then coated with a three-layered film consisting of an acid-soluble layer, a hydrophilic layer, and an ...
http://ijpsr.com/bft-article/a-review-on-colon-targeted-drug-delivery-system/?view=fulltext
A REVIEW ON COLON TARGETED DRUG DELIVERY SYSTEM HTML Full Text. A REVIEW ON COLON TARGETED DRUG DELIVERY SYSTEM. Anita * 1, Anil Singh 1 and Ankit Dabral 2. Himalayan Garhwal University 1, Dhaid Gaon, Shiv Nagar, Block Pokhara, Pauri Garhwal - 246169, Uttarakhand, India.. Shri Guru Ram Rai Institute of Technology and Science 2, Dehradun - 248121, Uttarakhand, …
https://www.researchgate.net/publication/315655561_Colon_targeted_drug_delivery_system_A_review
The colon targeted drug delivery system i s used for the treatment of various diseases related to colon like Crohn's disease, ulcerative colitis, etc and systemic delivery of therapeutic peptides ...
http://www.jpsbr.org/index_htm_files/5.pdf
COLON TARGETED DRUG DELIVERY SYSTEM: A REVIEW SYSTEM ABSTRACT ... means for targeted colon drug delivery[9]. There is a pH gradient in the gastrointestinal tract with value ranging from 1.2 in the stomach through 6.6 in the proximal small intestine to a peak of about
https://www.sciencedirect.com/science/article/pii/S1549963415000684
Colon targeted drug delivery is an active area of research for local diseases affecting the colon, as it improves the efficacy of therapeutics and enables localized treatment, which reduces systemic toxicity. ... Current oral nano-delivery system strategies for drug delivery to inflamed colon. Improved oral drug delivery design has drastically ...Author: Susan Hua, Ellen Marks, Jennifer J. Schneider, Simon Keely
https://www.slideshare.net/bharathpharmacist/colon-specific-drug-delivery-system-39685838
Sep 30, 2014 · CONTENTS :- Introduction Factors to be considered in the design of colon specific drug delivery system. Drug absorption in the colon. Approaches to colon-specific drug delivery . Evaluation of colon specific drug delivery systems 3. Introduction:- Definition:-Colon drug delivery system refers to targeted delivery of drug in to the lower parts ...
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