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https://www.slideshare.net/bharathpharmacist/colon-specific-drug-delivery-system-39685838
Sep 30, 2014 · Drug absorption in the colon. Approaches to colon-specific drug delivery . Evaluation of colon specific drug delivery systems 3. Introduction:- Definition:-Colon drug delivery system refers to targeted delivery of drug in to the lower parts of GI tract , mainly large intestine.
https://pharmawiki.in/ppt-colon-specific-drug-delivery/
[PPT] Colon Specific Drug Delivery. Contents of the powerpoint on Colon Specific Drug Delivery include: Introduction Advantages and Disadvantanges Techniques. Share this: Click to share on Twitter (Opens in new window) Click to share on Facebook (Opens in new window)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852048/
In recent times, colon targeted drug delivery systems have gained importance for the systemic delivery of protein and peptide drugs. This is because the peptide and protein drugs get destroyed or inactivated in acidic environment of the stomach or by pancreatic enzymes in the small intestine.
http://shodhganga.inflibnet.ac.in/bitstream/10603/8337/8/08_chapter%201.pdf
1: INTRODUCTION: 1.1 COLON SPECIFIC DRUG DELIVERY SYSTEM (CSDDS) The major goal of any drug delivery system is to supply a therapeutic amount of drug to a target site in a body, so that the desired drug concentration can be achieved swiftly and then maintained.
http://www.authorstream.com/Presentation/chinmayeechinni-1521280-colon-drug-delivery-system/
Aug 29, 2012 · INTRODUCTION Definition:-Colon drug delivery system refers to targeted delivery of drug in to the lower parts of GI tract , mainly large intestine. POTENTIAL APPLICATIONS OF CDDS: POTENTIAL APPLICATIONS OF CDDS Chronotherapy.
http://www.authorstream.com/Presentation/Dhavalrx-1470748-colon-specific-drug-delivery-system-dhaval/
Jul 12, 2012 · Rationale of colon drug delivery system Treatment of local pathologies. Chronotherapy (asthma, hypertension, cardiac arrhythmias, arthritis or inflammation) Site for delivery delicate drugs (Proteins and Peptides). Less enzymatic activity.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215502/
Feb 07, 2010 · Drug Delivery Index (DDI) and Clinical Evaluation of Colon-Specific Drug Delivery Systems DDI is a calculated pharmacokinetic parameter, following single or multiple dose of oral colonic prodrugs. DDI is the relative ratio of RCE (Relative colonic tissue exposure to the drug) to RSC (Relative amount of drug in blood i.e. that is relative systemic exposal to the drug).Author: Anil K. Philip, Betty Philip
https://pharmawiki.in/ppt-evaluation-of-oral-controlled-drug-delivery-systems/
Jan 13, 2014 · Contents of the powerpoint on Evaluation of Oral Controlled drug delivery systems include: INTRODUCTION ADVANTAGES AND DISADVANTAGES ATTRIBUTES OF DRUG CANDIDATE FOR CONTROLLED RELEASE SYSTEMS INVITRO-INVIVO EVALUATION OF FLOATING DRUG DELIVERY SYSTEM BIOADHESIVE DRUG DELIVERY SYSTEM BUCCAL BIOADHESIVE DRUG DELIVERY SYSTEM COLON SPECIFIC DRUG DELIVERY …
https://www.slideshare.net/GajananSanap/colon-targeted-drug-delivery-systems
Feb 27, 2016 · Azo polymeric new drug In which use of polymers as drug carriers for drug delivery to colon . Synthetic, naturally, sub-synthetic polymers used form colon targeted polymeric prodrug with azo linkage between polymer & drug moiety. The various azo polymers are evaluated for coating materials over drug …
http://www.thepharmajournal.com/vol1Issue7/Issue_sept_2012/3.3.pdf
1.4.2- pH in the colon. The pH of the GI tract is subject to both inter and intra subject variations. Diet, diseased state, and food intake influences the pH of the gastrointestinal fluid. The changes in the pH along the gastrointestinal tract have been used as a means for targeted colon drug delivery.
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