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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833276/
Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug Resistant Cancer Cells **Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
https://www.ncbi.nlm.nih.gov/pubmed/29690766
Jun 11, 2018 · Co-Delivery of Doxorubicin and Anti-BCL-2 siRNA by pH-Responsive Polymeric Vector to Overcome Drug Resistance in In Vitro and In Vivo HepG2 Hepatoma Model. Sun W(1)(2)(3), Chen X(1), Xie C(1), Wang Y(1), Lin L(4), Zhu K(4), Shuai X(1).Author: Weitong Sun, Weitong Sun, Xiaoyan Chen, Chao Xie, Yong Wang, Liteng Lin, Kangshun Zhu, Xintao Shuai
https://pubs.acs.org/doi/abs/10.1021/acs.biomac.8b00272
Co-Delivery of Doxorubicin and Anti-BCL-2 siRNA by pH-Responsive Polymeric Vector to Overcome Drug Resistance in In Vitro and In Vivo HepG2 Hepatoma Model Weitong Sun PCFM Lab of Ministry of Education, School of Materials Science and Engineering, Sun Yat-Sen University…Author: Weitong Sun, Weitong Sun, Xiaoyan Chen, Chao Xie, Yong Wang, Liteng Lin, Kangshun Zhu, Xintao Shuai
https://pubs.acs.org/doi/pdfplus/10.1021/acs.biomac.8b00272
Co-Delivery of Doxorubicin and Anti-BCL-2 siRNA by pH-Responsive Polymeric Vector to Overcome Drug Resistance in In Vitro and In Vivo HepG2 Hepatoma Model Weitong Sun † ‡ § ∥ , Xiaoyan Chen † ∥ , Chao Xie † , Yong Wang * † , Liteng Lin ⊥ , Kangshun Zhu * ⊥ , and Xintao Shuai * †
https://www.onlinelibrary.wiley.com/doi/10.1002/smll.200900621
Co‐delivery of Doxorubicin and Bcl‐2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug‐Resistant Cancer Cells † Alex M. Chen Department of Chemistry Rutgers, The State of New Jersey Newark, NJ 07102 (USA)Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
http://onlinelibrary.wiley.com/store/10.1002/smll.200900621/asset/supinfo/smll_200900621_sm_suppdata.pdf?v=1&s=1ee7d29e5ac46c1a25891315e52171888b655a5c
with Bcl-2 siRNA) in fresh cell growth medium (200 µl/well) were added. Control cells were added with equivalent volume of fresh media. Cells were cultured for 24 h before the cell viability assay was performed. The old medium was removed and 100 µl of fresh medium and 25 µl of a 5 mg/ml MTT (Fluka) solution in DPBS was added to each well.
https://www.academia.edu/11966316/Co_delivery_of_Doxorubicin_and_Bcl_2_siRNA_by_Mesoporous_Silica_Nanoparticles_Enhances_the_Efficacy_of_Chemotherapy_in_Multidrug_Resistant_Cancer_Cells
Co‐delivery of Doxorubicin and Bcl‐2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug‐Resistant Cancer Cells
https://www.ncbi.nlm.nih.gov/pubmed/24668891
Jul 09, 2014 · Co-delivery of chemotherapeutic drugs and siRNA to tumor cells is a vital means to silence drug resistant genes during the course of cancer chemotherapy for an improved chemotherapeutic effect. This study aims at effective co-delivery of siRNA and anticancer drugs to tumor cells.Author: Weicai Chen, Yuanyuan Yuan, Du Cheng, Jifeng Chen, Lu Wang, Xintao Shuai
https://www.nature.com/articles/srep23859
Mar 31, 2016 · NSC–PLL–PA micelles for co-delivery of Dox and siRNA (Dox–siRNA-micelle) were prepared by mixing Dox-micelle with a desired amount of siRNA in the same manner as described above. The sizes and morphology of the Dox–siRNA-micelle were investigated by transmission electron microscopy (TEM) (FEI,...Author: Chun-ge Zhang, Wen-jing Zhu, Yang Liu, Zhi-qiang Yuan, Shu-di Yang, Wei-liang Chen, Ji-zhao Li, Xiao...
https://www.sciencedirect.com/science/article/pii/S0142961211012610
The knockdown efficiency of BCL-2 gene at 25 n m siRNA was significantly higher than that at 12.5 n m siRNA. However, it reached saturation (ca. 90% inhibition) at the siRNA dose of 25 n m. Further increasing siRNA dose above this concentration did not make obvious difference in the BCL-2 gene suppression ( Fig. 3 ).Author: Du Cheng, Nuo Cao, Jifeng Chen, Xingsu Yu, Xintao Shuai
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