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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833276/
Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug Resistant Cancer Cells ** Dr. Alex M. Chen, Min Zhang, Dr. Dongguang Wei, Dr. Dirk Stueber, Dr. Oleh Taratula, Dr. Tamara Minko, Prof., and Dr. Huixin He, Prof.Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
https://www.ncbi.nlm.nih.gov/pubmed/29690766
Jun 11, 2018 · 1. Biomacromolecules. 2018 Jun 11;19(6):2248-2256. doi: 10.1021/acs.biomac.8b00272. Epub 2018 May 3. Co-Delivery of Doxorubicin and Anti-BCL-2 siRNA by pH-Responsive Polymeric Vector to Overcome Drug Resistance in In Vitro and In Vivo HepG2 Hepatoma Model.Author: Weitong Sun, Weitong Sun, Xiaoyan Chen, Chao Xie, Yong Wang, Liteng Lin, Kangshun Zhu, Xintao Shuai
https://www.onlinelibrary.wiley.com/doi/10.1002/smll.200900621
Co‐delivery of Doxorubicin and siRNAs by mesoporous silica nanoparticles into multidrug‐resistance cancer cells with minimal premature release significantly enhances the efficacy of chemotherapy by conquering the nonpump resistance and possibly bypassing the efflux pump resistance (see image).Author: Alex M. Chen, Min Zhang, Dongguang Wei, Dirk Stueber, Oleh Taratula, Tamara Minko, Huixin He
https://www.nature.com/articles/srep23859
Mar 31, 2016 · Chen, A. M. et al. Co-delivery of doxorubicin and bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer …Author: Chun-ge Zhang, Wen-jing Zhu, Yang Liu, Zhi-qiang Yuan, Shu-di Yang, Wei-liang Chen, Ji-zhao Li, Xiao...
https://pubs.acs.org/doi/full/10.1021/acs.biomac.8b00272
Co-Delivery of Doxorubicin and Anti-BCL-2 siRNA by pH-Responsive Polymeric Vector to Overcome Drug Resistance in In Vitro and In Vivo HepG2 Hepatoma Model. ... Co-delivery of curcumin and Bcl-2 siRNA by PAMAM dendrimers for enhancement of the therapeutic efficacy in HeLa cancer cells.Author: Weitong Sun, Weitong Sun, Xiaoyan Chen, Chao Xie, Yong Wang, Liteng Lin, Kangshun Zhu, Xintao Shuai
https://www.sciencedirect.com/science/article/pii/S0927776519309063
Co-delivery of therapeutic agents and small interfering RNA (siRNA) can be achieved by a suitable nanovehicle. In this work, the solubility and bioavailability of curcumin (Cur) were enhanced by entrapment in a polyamidoamine (PAMAM) dendrimer, and a polyplex was formed by grafting Bcl-2 siRNA onto the surface amine groups to produce PAMAM-Cur/Bcl-2 siRNA nanoparticles (NPs).Author: Maryam Ghaffari, Maryam Ghaffari, Gholamreza Dehghan, Behzad Baradaran, Amir Zarebkohan, Behzad Mans...
https://www.sciencedirect.com/science/article/pii/S0142961211012610
Multifunctional nanocarrier mediated co-delivery of doxorubicin and siRNA for synergistic enhancement of glioma apoptosis in rat. ... O. Taratula, T. Minko, et al.Co-delivery of doxorubicin and bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells. Small, 5 (2009), pp. 2673-2677.Author: Du Cheng, Nuo Cao, Jifeng Chen, Xingsu Yu, Xintao Shuai
https://pubs.acs.org/doi/abs/10.1021/acs.biomac.8b00272
Co-Delivery of Doxorubicin and Anti-BCL-2 siRNA by pH-Responsive Polymeric Vector to Overcome Drug Resistance in In Vitro and In Vivo HepG2 Hepatoma ModelAuthor: Weitong Sun, Weitong Sun, Xiaoyan Chen, Chao Xie, Yong Wang, Liteng Lin, Kangshun Zhu, Xintao Shuai
http://onlinelibrary.wiley.com/store/10.1002/smll.200900621/asset/supinfo/smll_200900621_sm_suppdata.pdf?v=1&s=1ee7d29e5ac46c1a25891315e52171888b655a5c
G2 amine-terminated PAMAM dendrimer, doxorubicin hydrochloride and other chemicals used in this study were purchased from Sigma Aldrich (Milwaukee, WI), and used without further purification. siRNA that are sequence specific for human Bcl-2 mRNA was custom synthesized by Ambion (Austin, TX).
https://www.academia.edu/11966316/Co_delivery_of_Doxorubicin_and_Bcl_2_siRNA_by_Mesoporous_Silica_Nanoparticles_Enhances_the_Efficacy_of_Chemotherapy_in_Multidrug_Resistant_Cancer_Cells
Co‐delivery of Doxorubicin and Bcl‐2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug‐Resistant Cancer Cells
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