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http://indus.org/healthcare/Secientific%20Sessions/Dr.%20G.D.%20Puri%20-%20Closed%20Loop%20Anaesthesia%20Delivery%20System%20(CLADS).pdf
Closed Loop Anaesthesia Delivery System (CLADS) -Anaesthesia Robot Prof. G. D. Puri Keywords: Anaesthesia, closed loop anaesthesia, propofol, EEG, BIS Anaesthesia practice in operating room primarily involves giving anaesthetics drugs to patients to produce unconsciousness and ensuring safe surgery without any untoward incidence.File Size: 372KB
http://www.clads-iaads.com/
A closed loop anaesthesia delivery system (CLADS) has been developed at PGI with the uniqueness of using simple syringe pumps to control the intravenous anaesthetic drug delivery and for the first time using closed loop administration of anaesthetics both for induction as …
https://www.ncbi.nlm.nih.gov/pubmed/17591128
Closed loop anaesthetic delivery using our patented system led to lower induction doses of propofol (P < 0.05) and less overshoot of the target BIS (P < 0.05). The closed loop system maintained BIS to within +/-10 of target for a significantly longer time during the maintenance phase of anaesthesia (P < 0.01).Author: Puri Gd, Kumar B, Aveek J
https://journals.lww.com/anesthesia-analgesia/Fulltext/2016/01000/A_Multicenter_Evaluation_of_a_Closed_Loop.21.aspx
Closed-loop anesthesia delivery system (CLADS) is a locally developed BIS–guided, closed-loop anesthesia delivery system. It has been used successfully for automated administration of propofol in various situations, such as noncardiac surgery, 7 cardiac surgery, 10 postoperative sedation, 11 and high-altitude sugery. 12 However, all these ...
https://journals.lww.com/anesthesia-analgesia/Fulltext/2017/02000/Closed_Loop_Delivery_Systems_Versus_Manually.16.aspx
esthesia. Scopus, PubMed, EMBASE, and the Cochrane Central Register of clinical trials were searched for pertinent studies. Inclusion criteria were random allocation to treatment and closed-loop delivery systems versus manually controlled administration of total IV anesthesia in any surgical setting. Exclusion criteria were duplicate publications and nonadult studies. Twelve studies were ...
https://www.ncbi.nlm.nih.gov/pubmed/25902324/
A Multicenter Evaluation of a Closed-Loop Anesthesia Delivery System: A Randomized Controlled Trial. Puri GD(1), Mathew PJ, Biswas I, Dutta A, Sood J, Gombar S, Palta S, Tsering M, Gautam PL, Jayant A, Arora I, Bajaj V, Punia TS, Singh G.Author: Goverdhan D. Puri, Preethy J. Mathew, Indranil Biswas, Amitabh Dutta, Jayashree Sood, Satinder Gomba...
https://www.sciencedirect.com/science/article/pii/S0952818017300697
Closed loop anesthesia delivery system has not been previously studied in patients with left ventricular systolic dysfunction. • This study compares CLADS a closed loop anesthesia system with target controlled infusion system (Marsh model) using BIS for anaesthesia depth control in patients with low EF.Author: V. Mahajan, T. Samra, G.D. Puri
https://clinicaltrials.gov/ct2/show/NCT01771263
The investigators aim to demonstrate that closed-loop control of anesthesia and analgesia based on EEG feedback is clinically feasible. This pilot study will help us take a significant step towards a controlled trial in which the clinical benefit of this method of closed-loop control of anesthesia can be assessed.
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2755340
The dual proportional-integral-derivative algorithm of the closed-loop system was used to deliver a target controlled infusion of propofol and remifentanil during induction and maintenance of anesthesia in order to maintain BIS values between 40 and 60.Author: Alexandre Joosten, Joseph Rinehart, Aurélie Bardaji, Philippe Van der Linden, Vincent Jame, Luc Van ...
https://sites.lafayette.edu/che324-sp17/2017/03/17/is-automated-closed-loop-controlled-propofol-delivery-system-a-fantasy-or-reality/
The use of an automated closed-loop controlled Propofol delivery system using BIS monitoring reduces primary anesthetic use as well as emergence and recovery time. Experiment that utilized Propofol reveals that 13% to 23% less hypnotic drug was used and 35% to 40% quicker wake up was obtained, which significantly reduces the cost of clinic.
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