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http://indus.org/healthcare/Secientific%20Sessions/Dr.%20G.D.%20Puri%20-%20Closed%20Loop%20Anaesthesia%20Delivery%20System%20(CLADS).pdf
Closed Loop Anaesthesia Delivery System (CLADS) -Anaesthesia Robot Prof. G. D. Puri Keywords: Anaesthesia, closed loop anaesthesia, propofol, EEG, BIS Anaesthesia practice in operating room primarily involves giving anaesthetics drugs to patients to produce unconsciousness and ensuring safe surgery without any untoward incidence.File Size: 372KB
http://www.clads-iaads.com/
A closed loop anaesthesia delivery system (CLADS) has been developed at PGI with the uniqueness of using simple syringe pumps to control the intravenous anaesthetic drug delivery and for the first time using closed loop administration of anaesthetics both for induction as …
https://www.ncbi.nlm.nih.gov/pubmed/17591128
Closed loop anaesthetic delivery using our patented system led to lower induction doses of propofol (P < 0.05) and less overshoot of the target BIS (P < 0.05). The closed loop system maintained BIS to within +/-10 of target for a significantly longer time during the maintenance phase of anaesthesia (P < 0.01).Author: Puri Gd, Kumar B, Aveek J
https://journals.lww.com/anesthesia-analgesia/Fulltext/2013/11000/Closed_Loop_Systems_in_Anesthesia___Reality_or.3.aspx
A closed-loop system is a control system with a feedback loop that automatically changes the output based on differences to the input signal. Most naturally occurring control systems are closed-loop systems. In engineering, an example of a simple closed-loop system would be the use of a thermostat to regulate room temperature.
https://clinicaltrials.gov/ct2/show/NCT01771263
The investigators aim to demonstrate that closed-loop control of anesthesia and analgesia based on EEG feedback is clinically feasible. This pilot study will help us take a significant step towards a controlled trial in which the clinical benefit of this method of closed-loop control of anesthesia can be assessed.
https://academic.oup.com/bja/article/110/6/1031/245822
Feb 20, 2013 · McSleepy is an automated, expert-based closed-loop anaesthesia drug delivery system that integrates the three components of general anaesthesia: hypnosis, analgesia, and muscle relaxation. The BIS was used as the control variable for hypnosis in order to calculate propofol infusion rates to maintain a pre-determined target set-point.Author: T.M. Hemmerling, E. Arbeid, M. Wehbe, S. Cyr, R. Taddei, C. Zaouter
https://www.sciencedirect.com/science/article/pii/S0952818017300697
Closed loop anesthesia delivery system has not been previously studied in patients with left ventricular systolic dysfunction. • This study compares CLADS a closed loop anesthesia system with target controlled infusion system (Marsh model) using BIS for anaesthesia depth control in patients with low EF.Author: V. Mahajan, T. Samra, G.D. Puri
https://onlinelibrary.wiley.com/doi/10.1111/pan.12265
Methods. Forty ASA II‐III children, undergoing elective cardiac surgery under cardiopulmonary bypass (CPB) in a tertiary care hospital, were randomized to receive propofol either through a closed‐loop anesthesia delivery system (CL group) or through traditional manual …Author: Indranil Biswas, Preethy J. Mathew, Rana S. Singh, Goverdhan D. Puri
https://journals.lww.com/anesthesia-analgesia/Fulltext/2017/02000/Closed_Loop_Delivery_Systems_Versus_Manually.16.aspx
Bispectral Index Scale (BIS)-guided closed-loop delivery of anesthetics has been extensively studied. We performed a meta-analysis of all the randomized clinical trials comparing efficacy and performance between BIS-guided closed-loop delivery and manually controlled administration of total IV anesthesia.
https://www.ncbi.nlm.nih.gov/pubmed/25902324/
A Multicenter Evaluation of a Closed-Loop Anesthesia Delivery System: A Randomized Controlled Trial. Puri GD(1), Mathew PJ, Biswas I, Dutta A, Sood J, Gombar S, Palta S, Tsering M, Gautam PL, Jayant A, Arora I, Bajaj V, Punia TS, Singh G.Author: Goverdhan D. Puri, Preethy J. Mathew, Indranil Biswas, Amitabh Dutta, Jayashree Sood, Satinder Gomba...
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