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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374549/
Colon and intestinal drug delivery: Since, chitosan is degraded by the microflora that are available in the colon it was found to be promising for colon-specific drug delivery. Chitosan esters, such as chitosan succinate and chitosan phthalate have been used successfully as potential matrices for the colon-specific oral delivery of diclofenac ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975351/
Feb 26, 2014 · Docetaxel-Loaded Chitosan Microspheres as a Lung Targeted Drug Delivery System: ... In case of targeted drug delivery system such as microspheres, major portion of the drug and excipient are accumulated in specific tissue (lung) and therefore, determining the compatibility between these tissues and the microspheres formulation becomes a ...Author: Hao Wang, Yongdong Xu, Xiao Zhou
https://www.sciencedirect.com/science/article/pii/S0168365997002034
Design of microencapsulated chitosan microspheres for colonic drug delivery. ... Among the different approaches to achieve colon-selective drug delivery, the use of polymers, specifically biodegraded by colonic bacteria, holds great promise. In this work a new system which combines specific biodegradability and pH-dependent release is presented ...Author: M.L Lorenzo-Lamosa, C Remuñán-López, J.L Vila-Jato, M.J Alonso
https://www.researchgate.net/publication/227179734_Chitosan_Microspheres_in_Novel_Drug_Delivery_Systems
focuses on the preparation, characterization of chitosan microspheres and their role in nov el drug delivery systems. Key words: Biopolymer , bio-compatible, coacervation, chitosan, drug targeting ...
https://www.hindawi.com/journals/bmri/2017/3564060/
Thermosensitive hydrogels have increasingly received considerable attention for local drug delivery based on many advantages. However, burst release of drugs is becoming a critical challenge when the hydrogels are employed. Microspheres- (MS-) loaded thermosensitive hydrogels were thus fabricated to address this limitation. Employing an orthogonal design, the spray-dried operations of ...Author: Ting-Ting Yang, Yuan-Zheng Cheng, Meng Qin, Yong-Hong Wang, Hong-Li Yu, An-Lin Wang, Wei-Fen Zhang
https://www.sciencedirect.com/science/article/pii/S0939641112001038
Due to its nontoxic character, permeation enhancing properties, and physicochemical characteristics, chitosan is a suitable material for the design of ocular drug delivery systems. Chitosan-based formulations used for ophthalmic drug delivery are hydrogels , nanoparticles , and coated colloidal systems . Chitosan-based systems have the ...Author: Andreas Bernkop-Schnürch, Sarah Dünnhaupt
https://www.hindawi.com/journals/bmri/2018/9073420/
2.3. Yield, Encapsulation Efficiency, and Drug Load. The spray-dried microspheres were collected and the YD account as the following: where represents the total mass of microspheres and represents the quantity of the total added solid components.. The drug contents of the microspheres were determined using a UV (UV-1700, Shimadzu, Japan) spectrophotometer at 286 nm.Author: Hong-Li Yu, Zhan-Qin Feng, Jing-Jing Zhang, Yong-Hong Wang, De-Jun Ding, Yuan-Yuan Gao, Wei-Fen Zhan...
http://www.nephro-pathology.com/uploads/1/0/0/4/10044970/chitosan_mediated_targeted_drug_delivery.pdf
intravenous injection for targeted drug delivery. Conjugation of the targeting moieties to the surface of drug-loaded nanoparticles may improve therapeutic efficiency of the drug [24]. Chitosan has been widely utilized as drug delivery systems for low molecular drugs, peptides and genes [16, 25, 26]. Despite the recent emergence of
https://www.researchgate.net/publication/333616179_Chitin_and_Chitosan_in_Drug_Delivery
Chitosan-based NP have various applications in non-parenteral drug delivery for the treatment of cancer, gastrointestinal diseases, pulmonary diseases, drug delivery to the brain and ocular ...
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
Microspheres received much attention not only for prolonged release, but also for targeting of drugs. In future microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, genetic materials, targeted and effective drug delivery. The current aim of …File Size: 1MB
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