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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161066/
For both passive and iontophoretic drug delivery in general, the oral mucosa provides several advantages for systemic drug delivery over other routes of administration. For the treatment of oral diseases, local drug delivery to the tissues in the oral cavity has the advantage of direct drug application (e.g., topical application on the tissues) that can prevent systemic adverse effects.Author: Apipa Wanasathop, S. Kevin Li
https://www.sciencedirect.com/science/article/pii/S0169409X03002424
The Vyteris iontophoretic drug delivery system is designed to provide rapid local dermal anesthesia to minimize pain for medical procedures such as insertion of IV catheters, needle sticks for blood draws and other diagnostic procedures, and dermatological surgical procedures.Author: Yogeshvar N. Kalia, Aarti Naik, James Garrison, Richard H. Guy
https://www.sciencedirect.com/science/article/pii/S0928098718305268
In contrast, at pH 3, with the elevation in H 3 O + concentration, the skin now assumes a net positive charge, becoming anion-permselective, and the direction of electroosmotic flow is reversed – all factors now working against the iontophoretic delivery of a cationic drug from the anode.Author: Asma Djabri, Richard H. Guy, M. Begoña Delgado-Charro
https://www.ncbi.nlm.nih.gov/pubmed/26406291
Transdermal iontophoretic drug delivery: advances and challenges. Ita K(1). Author information: (1)a College of Pharmacy, Touro University , Mare Island-Vallejo , CA , USA. The stratum corneum continues to pose considerable impediment to transdermal drug delivery. One of the effective ways of circumventing this challenge is through the use of ...Author: Kevin B. Ita
https://www.iontodevice.com/hyperhidrosis/electronic-transdermal-iontophoretic-drug-delivery-t681.html
Mar 20, 2008 · Iontophoresis Drug Delivery For iontophoresis drug delivery a low mA or voltage is used and it works best with a direct current device. Also, the treatment time is set normally to 5 minutes, else the drug will almost completely "walk" through to the other electrode.
https://www.healthproductsforyou.com/p-iontopatch-electronic-transdermal-drug-delivery-system.html
IontoPatch Electronic Transdermal Iontophoretic Drug Delivery System is used primarily by physical therapists, sports medicine professionals and occupational therapists for site-specific therapy to treat a variety of conditions. It is a non-invasive alternative to injection.Brand: TEIKOKU PHARMA USA
https://www.researchgate.net/publication/280139168_Iontophoretic_Drug_Delivery_History_and_Applications
When the transdermal drug flux is controlled by the. device instead of the skin, delivery of the drug is more reproducible leading to smaller inter and. intrasubject variations, since the drug release from the device can be controlled accurately than the. permeability of the skin (Guy et al., 1992).
https://en.wikipedia.org/wiki/Iontophoresis
Iontophoresis is a process of transdermal drug delivery by use of a voltage gradient on the skin. Molecules are transported across the stratum corneum by electrophoresis and electroosmosis and the electric field can also increase the permeability of the skin. These phenomena, directly and indirectly, constitute active transport of matter due to an applied electric current. The transport is measured in units of chemical flux, commonly µmol/. Iontophoresis …
https://www.4mdmedical.com/travanti-iontopatch-electronic-transdermal-iontophoretic-drug-delivery-system.html
The IontoPatch is an extended time-released electronic transdermal (iontophoretic) drug delivery medical device manufactured and marketed by Travanti Medical®, a business unit of The Tapemark Company. It is a non-invasive alternative to an injection and is designed for the Physical Medicine and Rehabilitation Market.Brand: Travanti Medical
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