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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850492/
Chitosan-Mediated siRNA Delivery In Vitro: Effect of Polymer Molecular Weight, Concentration and Salt Forms Sunee Techaarpornkul , Sirirat Wongkupasert , Praneet Opanasopit , Auayporn Apirakaramwong , Jurairat Nunthanid , and Uracha RuktanonchaiAuthor: Sunee Techaarpornkul, Sirirat Wongkupasert, Praneet Opanasopit, Auayporn Apirakaramwong, Jurairat Nu...
https://www.ncbi.nlm.nih.gov/pubmed/20058108
Chitosan-mediated siRNA delivery in vitro: effect of polymer molecular weight, concentration and salt forms. Techaarpornkul S(1), Wongkupasert S, Opanasopit P, Apirakaramwong A, Nunthanid J, Ruktanonchai U. Author information: (1)Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.Author: Sunee Techaarpornkul, Sirirat Wongkupasert, Praneet Opanasopit, Auayporn Apirakaramwong, Jurairat Nu...
https://link.springer.com/article/10.1208/s12249-009-9355-6
Jan 08, 2010 · Chitosan-Mediated siRNA Delivery In Vitro: Effect of Polymer Molecular Weight, Concentration and Salt Forms. Sunee Techaarpornkul 1,Author: Sunee Techaarpornkul, Sirirat Wongkupasert, Praneet Opanasopit, Auayporn Apirakaramwong, Jurairat Nu...
https://www.researchgate.net/publication/40895999_Chitosan-Mediated_siRNA_Delivery_In_Vitro_Effect_of_Polymer_Molecular_Weight_Concentration_and_Salt_Forms
Chitosan-Mediated siRNA Delivery In Vitro: Effect of Polymer Molecular Weight, Concentration and Salt Forms
https://www.sciencedirect.com/science/article/pii/S1549963415002014
Chitosan is known to be an effective agent for siRNA complexation, and capable of delivery to various types of macrophages.26, 31, 39 Although the chitosan system does not specifically target any particular cell type, they are shown here to be internalized solely by microglia/macrophages in vivo. Transfection of cationic polyplexes mediated by charge interactions between the positive surface charge of the …Author: Andrew M. Louw, Mallappa K. Kolar, Liudmila N. Novikova, Paul J. Kingham, Mikael Wiberg, Jørgen Kjem...
https://www.nature.com/articles/nprot.2012.131
Nov 15, 2012 · We used immature dendritic cells (DCs) as a source of exosomes, as they have been reported to be immunologically inert 10, and we specifically targeted these exosomes to the brain by display of a rabies virus glycoprotein (RVG)–derived peptide, and then loaded them with siRNA for delivery, first in vitro then in vivo.Author: Samir El-Andaloussi, Samir El-Andaloussi, Yi Lee, Samira Lakhal-Littleton, Jinghuan Li, Yiqi Seow, C...
https://www.sciencedirect.com/science/article/pii/S1525001606001808
This work introduces a novel chitosan-based siRNA nanoparticle delivery system for RNA interference in vitro and in vivo. The formation of interpolyelectrolyte complexes between siRNA duplexes (21-mers) and chitosan polymer into nanoparticles, ranging from 40 to 600 nm, was shown using atomic force microscopy and photon correlation spectroscopy.Author: Kenneth Alan Howard, Ulrik Lytt Rahbek, Xiudong Liu, Christian Kroun Damgaard, Sys Zoffman Glud, Mor...
https://www.nature.com/articles/nbt739
Sep 16, 2002 · Recombinant adenoviruses were generated from the siGFP (pmCMVsiGFPmpA) and siβgluc (pmCMVsiβglucmpA) plasmids 18,19 to test the hypothesis that virally expressed siRNA allows for diminished gene expression of endogenous targets in vitro and in vivo.Author: Haibin Xia, Qinwen Mao, Henry L. Paulson, Beverly L. Davidson
https://www.researchgate.net/publication/283524319_Chitosan_Nanoparticles_for_SiRNA_Delivery_In_Vitro
Chitosan Nanoparticles for SiRNA Delivery In Vitro ... have been developed in vitro and in vivo for DNA and siRNA delivery systems because of their cationic charge, biodegradability and ...
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