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https://www.news-medical.net/health/Chemically-Controlled-Drug-Delivery-Systems.aspx
Mechanisms of Action. The use of chemically-controlled drug delivery systems relies on one of two main mechanisms: Bioerosion. The bioerosion system, also called the biodegradation system, is ...
https://ocw.mit.edu/courses/materials-science-and-engineering/3-051j-materials-for-biomedical-applications-spring-2006/lecture-notes/lecture18.pdf
Drug Delivery: Controlled Release Chemically-controlled Devices 3.051J/20.340J Materials for Biomedical Applications, Spring 2006 1. Drug Delivery System (DDS) Controlling delivery rate and Site-specific delivery of drugs Current drug administration Minimum effective level Toxic level
https://www.sciencedirect.com/science/article/pii/0168365988900375
Journal of Controlled Release, S (1988) 111-125 Eisevier Science Publishers B.V., Amsterdam Printed in The Netherlands Review 111 CHEMICALLY SELF-REGULATED DRUG DELIVERY SYSTEMS J. Heller Controlled Release and Biopolymer Program, SRI International, MenloPark, CA 94025 (U.S.A.) (Received February 16, 1988; accepted in revised form May 10, 1988) INTRODUCTION During the …Author: J. Heller
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
controlled drug delivery applications.Sixty million patients benefit from advanced drug delivery systems today, receiving safer and more effective doses of the medicines they need to fight a variety of human ailments, including cancer. Controlled Drug Delivery (CDD) occurs when a …
https://pdfs.semanticscholar.org/2079/b751e16d7a9d34d2e0604a35a312d5bca4b2.pdf
designing controlled drug delivery systems. Various routes of administration pose different challenges for product design. As a result of the different barriers and pathways involved, selection of an administration route is an important factor for design of drug delivery system. For example, the oral route is most widely utilized route because
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
From a drug delivery perspective, polymer devices can be categorized as diffusion-controlled (monolithic devices), solvent-activated (swelling- or osmotically-controlled devices ), chemically controlled (biodegradable), or externally-triggered systems (e.g., pH, temperature) .Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.slideshare.net/biswajitmaity5895/diffusion-controlled-systems-solventactivated-system-chemically-controlled-system-73850924
Mar 29, 2017 · CHEMICALLY CONTROLLED SYSTEM CHEMICALLY CONTROLLED SYSTEMS Pendant-chain system Drug,chemically linked to the backbone Chemical hydrolysis or enzymatic cleavage Linked directly or via a spacer group Bioerodable or biodegradable system Drug: uniformly dispersed Slow released as the polymer disintegrates No removal from the body Irrespective of ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/controlled-drug-release
Two types of controlled drug release can be achieved – temporal and distribution control. In temporal control, the aim of the drug delivery system is to deliver the drug over an extended period of time or at a specific duration during treatment.
http://www.authorstream.com/Presentation/ashanibasu-1962451-development-evaluation-implantable-drug-delivery-system/
Oct 15, 2013 · Chemically controlled drug delivery system Chemically controlled drug delivery systems regulate the drug release rate by a chemical reaction with the polymer. Principle Advantage:- The polymer is dissolved and absorbed by the body and there is no need for surgical removal of the device at the completion of drug delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568318/
Feb 05, 2013 · There are several relevant extensions of the technology platform. For example, more than one drug could be tethered to a hydrogel by one or more individually tuned linkers to provide a delivery system that releases the drug combination at the same or different rates.Author: Gary W. Ashley, Jeff Henise, Ralph Reid, Daniel V. Santi
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