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https://www.sciencedirect.com/science/article/pii/S016836590800463X
Chemically controlled closed-loop insulin delivery has been explored by two main strategies. The first one consists in delivering insulin with a glucose-responsive matrix. Polymeric hydrogels that swell or shrink according to the glucose concentration allow delivering insulin doses …Author: Valérie Ravaine, Valérie Ravaine, Christophe Ancla, Christophe Ancla, Bogdan Catargi
https://www.ncbi.nlm.nih.gov/pubmed/18782593
Nov 24, 2008 · Chemically controlled closed-loop insulin delivery has been explored by two main strategies. The first one consists in delivering insulin with a glucose-responsive matrix. Polymeric hydrogels that swell or shrink according to the glucose concentration allow delivering insulin doses adapted to the glucose concentration.Author: Valérie Ravaine, Valérie Ravaine, Christophe Ancla, Christophe Ancla, Bogdan Catargi
https://www.researchgate.net/publication/23248292_Chemically_controlled_closed-loop_insulin_delivery
Chemically controlled closed-loop insulin delivery has been explored by two main strategies. The first one consists in delivering insulin with a glucose-responsive matrix.
https://www.ncbi.nlm.nih.gov/pubmed/26051293
In this chapter, data from randomized controlled trials with closed-loop insulin delivery that included type 1 diabetes population are summarized, and an evidence-based vision for possible routine utilization of closed loop is provided.Author: Tadej Battelino, Tadej Battelino, Jasna Šuput Omladič, Moshe Phillip, Moshe Phillip
https://www.nature.com/articles/s41551-019-0508-y
Feb 03, 2020 · Brownlee, M. & Cerami, A. Glycosylated insulin complexed to concanavalin A: biochemical basis for a closed-loop insulin delivery system. Diabetes 32 , 499–504 (1983). CASAuthor: Jicheng Yu, Jinqiang Wang, Jinqiang Wang, Yuqi Zhang, Guojun Chen, Guojun Chen, Weiwei Mao, Yanqi Ye...
https://www.researchgate.net/publication/331053210_Glucose-Responsive_Insulin_Delivery_Microneedle-Array_Patch_Fabricated_with_Enzyme-Free_Polymeric_Components_Capable_of_On-Demand_Insulin_Delivery_Adv_Funct_Mater_72019
Chemically controlled closed-loop insulin delivery has been explored by two main strategies. The first one consists in delivering insulin with a glucose-responsive matrix.
https://www.innocentive.com/files/specific_examples_of_gris.pdf
Author's personal copy Review Chemically controlled closed-loop insulin delivery Valérie Ravainea,b,, Christophe Anclaa,b, Bogdan Catargic, a Université Bordeaux, Institut des Sciences Moléculaires, ENSCPB, 16 Av. Pey Berland, 33607, Pessac Cedex F33607, France b CNRS, Institut des Sciences Moléculaires, Talence Cedex, F33405, France c Université Bordeaux, Hôpital Haut-Lévêque, CHU de ...
https://einstein.pure.elsevier.com/en/publications/glycosylated-insulin-complexed-to-concanavalin-a-biochemical-basi-2
T1 - Glycosylated insulin complexed to concanavalin A. Biochemical basis for a closed-loop insulin delivery system. AU - Brownlee, M. AU - Cerami, A. PY - 1983/1/1. Y1 - 1983/1/1. N2 - The oligosaccharides maltose, maltotriose, mannotriose, and mannotetrose have been chemically attached to insulin molecules.Author: Michael Brownlee, Anthony Cerami
https://diabetes.diabetesjournals.org/content/32/6/499
Jun 01, 1983 · This aggregation phenomenon was found to be markedly inhibited when glycosylated insulins were synthesized utilizing partially sulfated insulin. Results from the studies described in this report provide the biochemical basis for a closed-loop, glucose-controlled insulin delivery system, utilizing glyco-sylated insulin complexed to Con A.Author: Michael Brownlee, Anthony Cerami
https://www.thefreelibrary.com/Smart+insulins.-a0359130422
Jan 31, 2014 · 3. Brownlee M, Cerami A. A glucose-controlled insulin-delivery system: semisynthetic insulin bound to lectin. Science 1979; 206: 1190-1. 4. Ravaine V, Ancla C, Catargi B. Chemically controlled closed-loop insulin delivery. Journal of Controlled Release 2008; 132: 2-11. 5.
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