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https://www.nature.com/articles/nbt1223
Jun 25, 2006 · Technologies that mediate targeted delivery of small interfering RNAs (siRNAs) are needed to improve their therapeutic efficacy and safety. Therefore, we have developed aptamer-siRNA chimeric RNAs ...Author: James O McNamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A ...
https://www.ncbi.nlm.nih.gov/pubmed/16823371
Technologies that mediate targeted delivery of small interfering RNAs (siRNAs) are needed to improve their therapeutic efficacy and safety. Therefore, we have developed aptamer-siRNA chimeric RNAs capable of cell type-specific binding and delivery of functional siRNAs into cells.Author: James O McNamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A ...
https://www.gene-quantification.de/mcnamara-sirna-2006.pdf
Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras James O McNamara II1,3, Eran R Andrechek2,3, Yong Wang1, Kristi D Viles1, Rachel E Rempel2, Eli Gilboa1, Bruce A Sullenger1 & Paloma H Giangrande1 Technologies that mediate targeted delivery of small interfering RNAs (siRNAs) are needed to improve their therapeutic efficacy
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(06)00358-3
This Journal Full Site. Advanced Search. Log in; RegisterAuthor: James O McNamara, Eran R Andrechek, Yong Wang, Kristi D Viles, Rachel E Rempel, Eli Gilboa, Bruce A ...
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(16)30309-2
Jan 01, 2014 · In addition to small chemotherapeutic agents, proteins (enzymes or toxins) have been functionalized with cell-type-specific aptamers for targeted delivery . The ribosomal toxin gelonin is a small N-glycosidase protein of approximately 28 kDa that causes cell death.Author: Jiehua Zhou, John J. Rossi
https://www.researchgate.net/publication/237683162_83_Cell-Type_Specific_Delivery_of_siRNAs_with_Aptamer-siRNA_Chimeras
Cell-Type Specific Delivery of siRNAs with Aptamer-siRNA Chimeras Article (PDF Available) in Molecular Therapy 13 · May 2006 with 107 Reads How we measure 'reads'
http://ccc.chem.pitt.edu/wipf/Current%20Literature/Julia_2.pdf
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras Julia Vargas November 25th, 2006 Sullenger, B. A. et al Duke Center for Translational Research,
https://www.researchgate.net/publication/6962426_Cell_type-specific_delivery_of_siRNAs_with_aptamer-siRNA_chimeras
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. ... we have developed aptamer-siRNA chimeric RNAs capable of cell type-specific binding and delivery of functional siRNAs into ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2248269/
We report a new strategy for cell-type-specific delivery of functional siRNAs into cells. The method involves the noncovalent attachment of siRNAs to ligand-conjugated oligodeoxynucleotides via nucleic acid base-paired interactions. The resulting complexes can be directly applied to cells, leading to specific cellular uptake and gene silencing.Author: Kexiong Zhang, Qiaoqiao Wang, Yanhua Xie, Gil Mor, Emanuela Sega, Philip S. Low, Yingqun Huang
https://www.thermofisher.com/us/en/home/references/ambion-tech-support/rnai-sirna/tech-notes/high-throughput-delivery-of-sirnas-examples.html
High Throughput Delivery of siRNAs: Examples ‹ TechNotes ... Finally, while maximum transfection efficiency and cell viability are cell type specific, siRNA delivery by both methods is highly reproducible. The adaptation of reverse transfection and electroporation for medium to high throughput applications makes it possible to deliver sets ...
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