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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409749/
Feb 17, 2019 · Through the nasal route, the drug can access the brain directly along the trigeminal and olfactory nerves, which are located in the upper part of the nasal cavity. Nanoemulsions are formulations belonging to the field of nanomedicine. ... CNS delivery through the nasal mucosa sometimes performs better than parenteral administration as well, as ...Author: Maria Cristina Bonferoni, Silvia Rossi, Giuseppina Sandri, Franca Ferrari, Elisabetta Gavini, Giovan...
https://drug-dev.com/cns-delivery-bypassing-the-bbb-drug-delivery-from-the-olfactory-mucosa-to-the-cns/
T.R. Shantha, MD, PhD, FACA, explores and explains how therapeutic and non- therapeutic agents can reach the brain, bypassing through the formidable BBB based on the unique microanatomic and physiologic characteristics of the nasal olfactory mucosal route and its CNS connections that allow transportation directly into the CNS.
https://www.ncbi.nlm.nih.gov/pubmed/28887135
Dec 28, 2017 · Over the last several decades, different drug delivery systems (DDSs) have been studied for targeting the brain by the nasal route. Novel DDSs such as nanoparticles (NPs), liposomes and polymeric micelles have gained potential as useful tools for targeting the brain without toxicity in nasal mucosa and central nervous system (CNS).Author: Abdur Rauf Khan, Mengrui Liu, Muhammad Wasim Khan, Guangxi Zhai
https://www.sciencedirect.com/science/article/pii/S0361923018303678
Intracellular and paracellular pathways of drug transport from nasal cavity to the CNS through olfactory neurons and supporting cells are ... Penetration enhancer techniques at nasal drug delivery route. ... S.V. Dhuria, L.R. Hanson, W.H. FreyIntranasal delivery to the central nervous system: mechanisms and experimental considerations. J ...Author: Franciska Erdő, Luca Anna Bors, Dániel Farkas, Ágnes Bajza, Sveinbjörn Gizurarson
http://www.thepharmajournal.com/vol2Issue1/Issue_march_2013/14.pdf
Nasal Drug Delivery: A Potential Route for Brain Targeting ... Present review highlights the potential of nasal mucosa as an administration route for targeting the central nervous system, the brain. Targeted drug delivery seeks to concentrate the medication in the tissues of
http://www.imedpub.com/articles/nasal-drug-delivery-an-approach-of-drug-delivery-through-nasal-route.pdf
Pelagia Research Library Nasal drug delivery: An approach of drug delivery through nasal route Sanjay Dey 1*, Beduin Mahanti1, Bhasakar Mazumder 2, Ananya Malgope 3 and Sandeepan ... neural pathway by which drug is transported directly from the nasal cavity to CNS (cerebrospinalAuthor: Sanjay Dey, Beduin Mahanti, Bhasakar Mazumder, Ananya Malgope, eepan Dasgupta
https://www.researchgate.net/publication/272771855_NASAL_ROUTE_A_NOVELISTIC_APPROACH_FOR_TARGETED_DRUG_DELIVERY_TO_CNS
PDF Drug delivery through nasal route has attracted the interest of scientific community as it has been potentially explored as an alternative route... Find, read and cite all the research you ...
https://www.slideshare.net/kawii/nasal-drug-delivery-system-41893460
Nov 22, 2014 · INTRODUCTION Administration of drug through nasal route is referred as Nasal drug delivery system. Nasal route is an alternative to invasive administrations and provides a direct access to the systemic circulation. Intranasal Medication administration offers a …
https://quizlet.com/395407645/central-nervous-system-delivery-of-drugs-intranasal-delivery-and-gene-therapy-flash-cards/
In recent years it has been appreciated that the intranasal route of delivery may have a unique direct pathway to the CNS as well. A significant line of investigation in this area is the potential for development of non-invasive delivery methods for large macromolecular protein and peptide biological therapeutics to the central nervous system.
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