Cell Penetrating Peptide Delivery

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Cell Penetrating Peptide - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/neuroscience/cell-penetrating-peptide
    Yousef Javadzadeh, Leila Azharshekoufeh Bahari, in Nano- and Microscale Drug Delivery Systems, 2017. 3.5 Cell-Penetrating Peptides. Cell-penetrating peptides (CPPs) are short peptide sequences with positive charge and rich in lysine or arginine.

Cell-Penetrating Peptide-Mediated Delivery of TALEN ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896395/
    Jan 20, 2014 · Cell-Penetrating Peptide-Mediated Delivery of TALEN Proteins via Bioconjugation for Genome Engineering. ... Here we show that conjugation of cell-penetrating poly-Arg peptides to a surface-exposed Cys residue present on each TAL effector repeat imparted cell-penetrating activity to purified TALEN proteins.Author: Jia Liu, Thomas Gaj, James T. Patterson, Shannon J. Sirk, Carlos F. Barbas

Cell-Penetrating Peptide-Mediated Delivery of Cas9 Protein ...

    https://www.ncbi.nlm.nih.gov/pubmed/27832534/
    Cell-Penetrating Peptide-Mediated Delivery of Cas9 Protein and Guide RNA for Genome Editing. Suresh B(1)(2), Ramakrishna S(3)(4), Kim H(5)(6)(7). Author information: (1)Department of Pharmacology and Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of …Author: Bharathi Suresh, Suresh Ramakrishna, Hyongbum Kim

Cell-Penetrating Peptide - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/cell-penetrating-peptide
    Helin Räägel, Margus Pooga, in Peptide and Protein Delivery, 2011. Cell-penetrating peptides (CPP) have emerged as effective transport vectors for various therapeutic compounds, including peptides and proteins. When attached to a therapeutic molecule, the uptake of CPP-cargo complexes facilitated mostly by an endocytic mechanism becomes both an advantage and a drawback.

cell penetrating peptides

    http://cell-penetrating-peptides.com/
    What are Cell-Penetrating Peptides? Cell-Penetrating Peptides (CPPs), also known as protein transduction domains (PTDs), membrane translocating sequences (MTSs), and Trojan peptides are short peptides (≤40 amino acids), with the ability to gain access to the interior of almost any cell. They are highly cationic and usually rich in arginine and lysine amino acids.

Cell-Penetrating Peptides: Design, Synthesis, and ...

    http://pubs.acs.org/doi/abs/10.1021/nn4057269
    The intrinsic property of cell-penetrating peptides (CPPs) to deliver therapeutic molecules (nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has indicated that they may be potential components of future drugs and disease diagnostic agents. These versatile peptides are simple to synthesize, functionalize, and characterize yet are able to deliver covalently or ...

Targeted Delivery of Cell Penetrating Peptide Virus-like ...

    https://www.nature.com/articles/s41598-018-26749-y
    May 31, 2018 · Thus, the main aim of this study was to screen for a cell penetrating peptide (CPP) for the development of a targeting vector for skin cancer. ... Targeted Delivery of Cell Penetrating Peptide ...Author: Bee Koon Gan, Chean Yeah Yong, Kok Lian Ho, Abdul Rahman Omar, Noorjahan Banu Alitheen, Wen Siang Ta...

Cell-penetrating peptide sequence and modification ...

    https://www.nature.com/articles/s41598-019-42456-8
    Apr 18, 2019 · Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines Sanjay G. Patel 1 …Author: Sanjay G. Patel, Edward J. Sayers, Lin He, Rohan Narayan, Thomas L. Williams, Emily M. Mills, Rudolf...

Cell-Penetrating Peptides: From Basic Research to Clinics ...

    https://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147(17)30017-2
    The presence of cell and tissue barriers together with the low biomembrane permeability of various therapeutics often hampers systemic drug distribution; thus, most of the available molecules are of limited therapeutic value. Opportunities to increase medicament concentrations in areas that are difficult to access now exist with the advent of cell-penetrating peptides (CPPs), which can ...Author: Giulia Guidotti, Liliana Brambilla, Daniela Rossi

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