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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · Liposomes for Use in Gene Delivery 1. Introduction. Liposomes are vesicular structures that can form via the accumulation... 2. Characteristics. Liposomes are generally formed by the self-assembly... 3. Cationic Lipids. A solution of cationic lipids, often formed with …Author: Daniel A. Balazs, Wt. Godbey
https://www.researchgate.net/publication/7471375_Cationic_liposomes_for_gene_delivery
cationic liposomes as gene ca rriers The first gene therapy clinical t rial was approved in 1989 and consisted of using tumour infilt rating lymphocytes, containing
https://www.tandfonline.com/doi/abs/10.1517/17425247.2.2.237
Jun 01, 2015 · Cationic liposome–DNA complexes (lipoplexes) constitute a potentially viable alternative to viral vectors for the delivery of therapeutic genes. This review will focus on various parameters governing lipoplex biological activity, from their mode of formation to invivo behaviour. Particular emphasis is given to the mechanism of interaction of lipoplexes with cells, in an attempt to dissect ...Author: Sérgio Simões, Ana Filipe, Henrique Faneca, Miguel Mano, Nuno Penacho, Nejat Düzgünes, Maria Pedroso...
https://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291521-3773%2819980803%2937%3A13/14%3C1768%3A%3AAID-ANIE1768%3E3.0.CO%3B2-4
Cationic liposomes are able to deliver nucleic acids to cells and are projected to be core technology for the emerging discipline of gene therapy. The problems that still have to be faced are presented here along with potential solutions.Author: Andrew D. Miller
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288823/
Nov 01, 2014 · Cationic liposomes (CLs) are studied worldwide as carriers of DNA and short interfering RNA (siRNA) for gene delivery and gene silencing, and related clinical trials are ongoing.Author: Cyrus R. Safinya, Kai K. Ewert, Ramsey N. Majzoub, Cecília Leal
https://www.hindawi.com/journals/jdd/2011/326497/
However, due to the fact that cationic liposomes can be inactivated in the presence of serum, are unstable upon storage, and exhibit some cytotoxicity both in vitro and in vivo, anionic liposomes have been studied as potential gene delivery vehicles [63–65].Author: Daniel A. Balazs, Wt. Godbey
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